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structure nameTHE CRYSTAL STRUCTURE OF M644G VARIANT OF DNA POL EPSILON CONTAINING CTP IN THE POLYMERASE ACTIVE SITE
(DNA polymerase epsilon catalytic subunit A)
referenceJohansson et al. 'Nucleic ? ? 2023
sourceSaccharomyces cerevisiae
experimentX-ray (resolution=2.60, R-factor=0.241)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family B, exonuclease do; DNA polymerase family B 969;
reference complex4m8o_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKR

Estimated binding specificities ?

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# IC=2.440 IC/col=0.610 n_of_columns=4 specificity:   
A |  69  69   8   1
C |   8   8  69   0
G |   8   8  11  87
T |  11  11   8   8
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updated Sat Aug 2 22:59:36 2025