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structure nameTHE CRYSTAL STRUCTURE OF M644G VARIANT OF DNA POL EPSILON CONTAINING DTTP IN THE POLYMERASE ACTIVE SITE
(DNA polymerase epsilon catalytic subunit A)
referenceJohansson et al. 'Nucleic ? ? 2023
sourceSaccharomyces cerevisiae
experimentX-ray (resolution=2.60, R-factor=0.222)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family B, exonuclease do; DNA polymerase family B 998;
reference complex4m8o_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTVNSYKR

Estimated binding specificities ?

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# IC=2.295 IC/col=0.574 n_of_columns=4 specificity:   
A |   9   7   7   9
C |  73   7   7   7
G |   7  73   7   7
T |   7   9  75  73
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updated Fri Jan 9 20:47:43 2026