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structure nameTHE CRYSTAL STRUCTURE OF N828V VARIANT OF DNA POL EPSILON CONTAINING DATP IN THE POLYMERASE ACTIVE SITE
(DNA polymerase epsilon catalytic subunit A)
referenceJohansson et al. 'Nucleic ? ? 2023
sourceSaccharomyces cerevisiae
experimentX-ray (resolution=2.70, R-factor=0.238)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family B, exonuclease do;
reference complex4m8o_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKRR

Estimated binding specificities ?

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# IC=2.635 IC/col=0.659 n_of_columns=4 specificity:   
A |  67  67   9   0
C |   9   9  67   0
G |   9   9  11  96
T |  11  11   9   0
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updated Fri Jan 9 20:48:19 2026