8h40_AEGXY : 3D-footprint complex

Interface of input file ?

structure name	CRYO-EM STRUCTURE OF THE TRANSCRIPTION ACTIVATION COMPLEX NTCA-TAC
experiment	NMR
structural superfamily	cAMP-binding domain-like;"Winged helix" DNA-binding domain;
reference complex	8h40_X
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8h40_A interface=149,151,165,166,220,223,390, afllpdlieiqrssfrwfleeglieelnsfspitdytgklelhflghnyklkepkysveeakrrdstyavqmyvptrllnketgdikeqevfigdlplmtdrgtfiingaervivnqivrspgvyykseidkngrrtysaslipnrgaWlKfetdrndlvwvriDKtrklsaqvllkalglsdneifdalrhpeyfqktiekegqfseeealmelyrklRpgEpptvlggqqlldsrffdpkrydlgrvgryklnkklrlsvpdtvrvltsgdilaavdylinleydigsiddidhlgnrrvrsvgellqnqvrvglnrleriirermtvsdaevltpaslvnpkplvaaikeffgssqlsqfmdqtnplaelthkrrlsalgpggltrEragfavrdihpshygricpietpegpnagligslatharvnqygfletpfrpvengrvrfdqpaaymtadeeddlrvapgdipvdengyiigpqvpvryrqefstttpeqvdyvavspvqivsvatsmipflehddanralmgsnmqrqavpllkperplvgtgleaqgardsgmvivsrtdgdvvyvdateirvrvsgqlptasgkstdngqltsqkgqeirytvskyqrsnqdtclnqkplvrigervvagqvladgssteggelalgqnivvaympwegynyedailiserlvqddiytsihiekyeiearqtklgpeeitreipnvgedalrqldeqgiirigawveagdilvgkvtpkgesdqppeekllraifgekardvrdnslrvpngekgrvvdvrlftreqgdelppganmvvrvyvaqkrkiqvgdkmagrhgnkgiisrilpiedmpylpdgspvdivlnplgvpsrmnvgqvfecllgwaghtlgvrfkitpfdemygeessrrivhgklqeardetgkdwvynpddpgkimvydgrtgeafdrpvtigvaymlklvhlvddkiharstgpyslvtqqplggkaqqggqrfgemevwaleafgaaytlqelltvksddmqgrnealnaivkgkaiprpgtpesfkvlmrelqslgldiavhkvetqadgssldv > 8h40_E interface= tnqfdyvkiglasperirqwgertlpngqvvgevtkpetinyrtlkpemdglfcerifgpakdwechcgkykrvrhrgivcercgvevtesrvrrhrmgyiklaapvahvwylkgipsyisilldmplrdveqivyfnsyvvlspgnaEtLtykqllsedqwleIEdqiysedsqlqgvevgigaeallrlladinleqeaeslreeigsakgqkraklIkrLrvidnfiatgskpewmvmtvipvippdlrpmvqldggrfatsdlndlyrrvinrnnrlarlqeilapeiivrnekrmlqeavdalidngrrgrtvvgannrplkslsdiiegkqgrfrqnllgkrvdysgrsvivvgpklkihqcglpremaielfqpfvinrlirSgmvnnikaakklisrndpsvwdvleevieghpvmlnraptlhrlgiqafepilvegraiqlhplvcpafnadfdgdqmavhvplslesqaearllmlasnnilspatgrpiitpsqdmvlgayyltaenpgatkgagkyfaslddvimafqqeqidlhayvyvrfdgdvesdqpdtepvkvttnedgsrtvlykyrrvredaqgnvisqyiyttpgrviynkaiqealas > 8h40_G interface=4,6,7,10,18,88,89,100,128,130,131,132,133,136,140,143,144,158,161,287, yteDsIRlyLqeigrirLlradeeielarkiadllelervrerlseklerdprdsewaeavqlplpafryrlhigrrakdkmvqsnlRLvvsiakkymnRglsfqdliqegslgliraaekfdhekgYkFSTYatWwirQaiTRaiadqsrtirlpvHlyEtisrikkttkllsqemgrkpteeeiatrmemtieklrfiaksaqlpisletpigkeedsrlgdfiesdgetpedqvsknllredlekvldslsprerdvlrlryglddgrmktleeigqifnvtrErirqieakalrklrhpnrnsvlkeyir > 8h40_X interface=163,166,168, vetfernktiffpgdpaervyfllkgavklsrvyeageeitvallrensvfgvlslltgnksdrfyhavaftpvellsapieqveqalkenpelsmlmlrglssrilqtemmietlahrdmgsrlvsfllilcrdfgvpcadgitidlklshqaiaeaigstRvtVtRllgdlrekkmisihkkkitvhkpvtlsr > 8h40_Y interface=162,163,164,167, vetfernktiffpgdpaervyfllkgavklsrvyeageeitvallrensvfgvlslltgnksdrfyhavaftpvellsapieqveqalkenpelsmlmlrglssrilqtemmietlahrdmgsrlvsfllilcrdfgvpcadgitidlklshqaiaeaigsTRVtvTrllgdlrekkmisihkkkitvhkpvtlsr
interface signature	WKDKREE/ELIEILS/DIRLLRLRYFSTYWQTRHEE/RVR/TRVT

Estimated binding specificities ?

contact

# IC=22.485 IC/col=0.459 n_of_columns=49

specificity:

A |   0  11  96   8  24  24  24  24   7   0  96  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   8  24   4   0   0  96   5  90  69   0   0   0   0  24  24   1   0
C |   0   9   0   7  24  24  24  24   8   0   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   7  24   1   0   0   0  10   1   9   0   0   0   0  24  24  90   0
G |  96  11   0  78  24  24  24  24   7   0   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   5  24   1  96   0   0   7   4   9   0  96  96  94  24  24   4   0
T |   0  65   0   3  24  24  24  24  74  96   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  76  24  90   0  96   0  74   1   9  96   0   0   2  24  24   1  96

scan!

home
updated Fri Aug 1 10:47:31 2025