8h40_AEGXY : 3D-footprint complex

Interface of input file ?

structure name	CRYO-EM STRUCTURE OF THE TRANSCRIPTION ACTIVATION COMPLEX NTCA-TAC
experiment	NMR
structural superfamily	cAMP-binding domain-like;"Winged helix" DNA-binding domain;
reference complex	8h40_X
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8h40_A interface=149,151,165,166,220,223,390, afllpdlieiqrssfrwfleeglieelnsfspitdytgklelhflghnyklkepkysveeakrrdstyavqmyvptrllnketgdikeqevfigdlplmtdrgtfiingaervivnqivrspgvyykseidkngrrtysaslipnrgaWlKfetdrndlvwvriDKtrklsaqvllkalglsdneifdalrhpeyfqktiekegqfseeealmelyrklRpgEpptvlggqqlldsrffdpkrydlgrvgryklnkklrlsvpdtvrvltsgdilaavdylinleydigsiddidhlgnrrvrsvgellqnqvrvglnrleriirermtvsdaevltpaslvnpkplvaaikeffgssqlsqfmdqtnplaelthkrrlsalgpggltrEragfavrdihpshygricpietpegpnagligslatharvnqygfletpfrpvengrvrfdqpaaymtadeeddlrvapgdipvdengyiigpqvpvryrqefstttpeqvdyvavspvqivsvatsmipflehddanralmgsnmqrqavpllkperplvgtgleaqgardsgmvivsrtdgdvvyvdateirvrvsgqlptasgkstdngqltsqkgqeirytvskyqrsnqdtclnqkplvrigervvagqvladgssteggelalgqnivvaympwegynyedailiserlvqddiytsihiekyeiearqtklgpeeitreipnvgedalrqldeqgiirigawveagdilvgkvtpkgesdqppeekllraifgekardvrdnslrvpngekgrvvdvrlftreqgdelppganmvvrvyvaqkrkiqvgdkmagrhgnkgiisrilpiedmpylpdgspvdivlnplgvpsrmnvgqvfecllgwaghtlgvrfkitpfdemygeessrrivhgklqeardetgkdwvynpddpgkimvydgrtgeafdrpvtigvaymlklvhlvddkiharstgpyslvtqqplggkaqqggqrfgemevwaleafgaaytlqelltvksddmqgrnealnaivkgkaiprpgtpesfkvlmrelqslgldiavhkvetqadgssldv > 8h40_E interface= tnqfdyvkiglasperirqwgertlpngqvvgevtkpetinyrtlkpemdglfcerifgpakdwechcgkykrvrhrgivcercgvevtesrvrrhrmgyiklaapvahvwylkgipsyisilldmplrdveqivyfnsyvvlspgnaEtLtykqllsedqwleIEdqiysedsqlqgvevgigaeallrlladinleqeaeslreeigsakgqkraklIkrLrvidnfiatgskpewmvmtvipvippdlrpmvqldggrfatsdlndlyrrvinrnnrlarlqeilapeiivrnekrmlqeavdalidngrrgrtvvgannrplkslsdiiegkqgrfrqnllgkrvdysgrsvivvgpklkihqcglpremaielfqpfvinrlirSgmvnnikaakklisrndpsvwdvleevieghpvmlnraptlhrlgiqafepilvegraiqlhplvcpafnadfdgdqmavhvplslesqaearllmlasnnilspatgrpiitpsqdmvlgayyltaenpgatkgagkyfaslddvimafqqeqidlhayvyvrfdgdvesdqpdtepvkvttnedgsrtvlykyrrvredaqgnvisqyiyttpgrviynkaiqealas > 8h40_G interface=4,6,7,10,18,88,89,100,128,130,131,132,133,136,140,143,144,158,161,287, yteDsIRlyLqeigrirLlradeeielarkiadllelervrerlseklerdprdsewaeavqlplpafryrlhigrrakdkmvqsnlRLvvsiakkymnRglsfqdliqegslgliraaekfdhekgYkFSTYatWwirQaiTRaiadqsrtirlpvHlyEtisrikkttkllsqemgrkpteeeiatrmemtieklrfiaksaqlpisletpigkeedsrlgdfiesdgetpedqvsknllredlekvldslsprerdvlrlryglddgrmktleeigqifnvtrErirqieakalrklrhpnrnsvlkeyir > 8h40_X interface=163,166,168, vetfernktiffpgdpaervyfllkgavklsrvyeageeitvallrensvfgvlslltgnksdrfyhavaftpvellsapieqveqalkenpelsmlmlrglssrilqtemmietlahrdmgsrlvsfllilcrdfgvpcadgitidlklshqaiaeaigstRvtVtRllgdlrekkmisihkkkitvhkpvtlsr > 8h40_Y interface=162,163,164,167, vetfernktiffpgdpaervyfllkgavklsrvyeageeitvallrensvfgvlslltgnksdrfyhavaftpvellsapieqveqalkenpelsmlmlrglssrilqtemmietlahrdmgsrlvsfllilcrdfgvpcadgitidlklshqaiaeaigsTRVtvTrllgdlrekkmisihkkkitvhkpvtlsr
interface signature	WKDKREE/ELIEILS/DIRLLRLRYFSTYWQTRHEE/RVR/TRVT

Estimated binding specificities ?

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# IC=22.569 IC/col=0.461 n_of_columns=49

specificity:

A |   0   1  24  24   1   0   0   0  11   4  71  96  96   0  94  24  76  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0  96  73  24  24  24  24   8   0  69   0
C |   0   1  24  24   0  96  96   0   9   1   9   0   0  96   0  24   5  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0   0   9  24  24  24  24  74   0   9  96
G |   0  90  24  24   1   0   0  96   5  90   7   0   0   0   1  24  10  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0   0   7  24  24  24  24   7   0   9   0
T |  96   4  24  24  94   0   0   0  71   1   9   0   0   0   1  24   5  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  96   0   7  24  24  24  24   7  96   9   0

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updated Sat Jun 27 11:35:44 2026