8hih_CDFGNOPQ : 3D-footprint complex

Interface of input file ?

structure name	CRYO-EM STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS TRANSCRIPTION INITIATION COMPLEX WITH TRANSCRIPTION FACTOR GLNR
experiment	NMR
structural superfamily	C-terminal effector domain of the bipartite response regulators;CheY-like;
reference complex	8hih_Q
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8hih_C interface=152,174,179,181,182,198,256,276,392,434,437,438, nsvpgapnrvsfaklreplevpglldvqtdsfewligsprwresaaergdvnpvggleevlyelspiedfsgsmslsfsdprfddvkapvdeckdkdmtyaaplfvtaefinnntgeiksqtvfmgdfpmmtekgtfiingtervvvsqlvRspgvyfdetidkstdktlhsvKvipsRgAWlefdvdkrdtvgvriDrkrrqpvtvllkalgwtseqiverfgfseimrstlekdntvgtdealldiyrklrpgEpptkesaqtllenlffkekRydlarvgrykvnkklglhvgepitsstlteedvvatieylvrlhegqttmtvpggvevpvetddidhfgnrrlrtvgeliqnqirvgmsrmervvrermttqdveaitpqtliniRpvvaaikeffgtsqlsqfmdqnnplsglthkrrlsalgpggLsrERaglevrdvhpshygrmcpietpegpnigligslsvyarvnpfgfietpyrkvvdgvvsdeivyltadeedrhvvaqanspidadgrfveprvlvrrkageveyvpssevdymdvsprqmvsvatamipflehddanralmganmqrqavplvrseaplvgtgmelraaidagdvvvaeesgvieevsadyitvmhdngtrrtyrmrkfarsnhgtcanqcpivdagdrveagqviadgpctddgemalgknllvaimpweghnyedaiilsnrlveedvltsihieeheidardtklgaeeitrdipnisdevladldergivrigaevrdgdilvgkvtpkgeteltpeerllraifgekarevrdtslkvphgesgkvigirvfsrededelpagvnelvrvyvaqkrkisdgdklagrhgnkgvigkilpvedmpfladgtpvdiilnthgvprrmnigqilethlgwcahsgwkvdaakgvpdwaarlpdelleaqpnaivstpvfdgaqeaelqgllsctlpnrdgdvlvdadgkamlfdgrsgepfpypvtvgymyimklhhlvddkiharstgpysmitqqplggkaqfggqrfgemecwamqaygaaytlqelltiksddtvgrvkvyeaivkgenipepgipesfkvllkelqslclnvevlss > 8hih_D interface=287,288,330,331,334,389,427,501,502,864,867,868, mldvnffdelriglataedirqwsygevkkpetinyrtlkpekdglfcekifgptrdwecycgkykrvrfkgiicercgvevtrakvrrermghielaapvthiwyfkgvpsrlgylldlapkdlekiiyfaayvitsvdeemrhnelstleaemaverkavedqrdgelearaqkleadlaeleaegakadarrkvrdggeremrqirdraqreldrlediwstftklapkqlivdenlyrelvdrygeyftgamgaesiqklienfdidaeaeslrdvirngkgQKklralkrlkvvaafqqsgnspmgmvldavpvippelrpmvqLDggRfatsdlndlyrrvinrnnrlkrlidlgapeiivnnekrmlqesvdalfdngrrgRpvtgpgnrplkslsdllkgkqgrfrqnllgkrvdysgRsvivvgpqlklhqcglpklmalelfkpfvmkrlvdlnhaqniksakrmverqrpqvwdvleeviaehpvllnrAPtlhrlgiqafepmlvegkaiqlhplvceafnadfdgdqmavhlplsaeaqaearilmlssnnilspasgrplamprldmvtglyylttevpgdtgeyqpasgdhpetgvysspaeaimaadrgvlsvrakikvrltqlrppveieaelfghsgwqpgdawmaettlgrvmfnellplgypfvnkqmhkkvqaaiindlaerypmivvaqtvdklkdagfywatrsgvtvsmadvlvpprkkeildhyeeradkvekqfqrgalnhdernealveiwkeatdevgqalrehypddnpiitivdsgatgnftqtrtlagmkglvtnpkgefiprpvkssfregltvleyfinthgarkgladtAlrTAdsgyltrrlvdvsqdvivrehdcqtergivvelaerapdgtlirdpyietsayartlgtdavdeagnvivergqdlgdpeidallaagitqvkvrsvltcatstgvcatcygrsmatgklvdigeavgivaaqsigepgtqltmrtditgglprvqelfearvprgkapiadvtgrvrledgerfykitivpddggeevvydkiskrqrlrvfkrvlsdgdhvevgqqlmegsadphevlrvqgprevqihlvrevqevyraqgvsihdkhievivrqmlrrvtiidsgsteflpgslidraefeaenrrvvaeggepaagrpvlmgitkaslatdswlsaasfqettrvltdaaincrsdklnglkenviigklipagtginryrniavqpteearaaa > 8hih_F interface=21,23,24,27,30,35,94,96,97,108,112,130,131,134,136,139,140,141,143,144,145,147,148,152,159,165,166,169,172,179,214,216,220,224,225,227,233, edesealrqarkdaeltasaDsVRayLkqIgkvaLlnaeeevelakrieaglyatqlmtelsergeklpaaqrrdmmwicrdgdraknhlleaNlRLvvslakrytgRgmaFldliqegnlgliravekFDytKgYkfSTYaTWWiRQaitRamadqaRtiripVHmvEviNklgriqRellqdlgreptpeelakemditpekvleiqqyarEpIsldQtigDEgDsqlgdFiedseavvavdavsftllqdqlqsvldtlsereagvvrlrfgltdgqprtldeigqvygvtrerirqiesktmsklrhpsrsqvlrdyl > 8hih_G interface=40,41, alpiddldltvrsynclkregvhtvgelvartesdlldiRNfgqksidevkiklhql > 8hih_N interface=182,183,185,186,190, mlelllltselypdpvlpalsllphtvrtapaeasslleagnadavlvdarndlssgrglcrllsstgrsipvlavvsegglvavsadwgldeilllstgpaeidarlrlvvgdqeslgkvslgelvidegtytarlrgrpldltykefellkylaqhagrvftraqllhevwgydffggtRTvDVhvrRlraklgpehealigtvrnvgykavrpa > 8hih_O interface=182,183,185,186,187,189,190, mlelllltselypdpvlpalsllphtvrtapaeasslleagnadavlvdarndlssgrglcrllsstgrsipvlavvsegglvavsadwgldeilllstgpaeidarlrlvvgdqeslgkvslgelvidegtytarlrgrpldltykefellkylaqhagrvftraqllhevwgydffggtRTvDVHvRRlraklgpehealigtvrnvgykavrpa > 8hih_P interface=178,185,203, mlelllltselypdpvlpalsllphtvrtapaeasslleagnadavlvdarndlssgrglcrllsstgrsipvlavvsegglvavsadwgldeilllstgpaeidarlrlvvglgkvslgelvidegtytarlrgrpldltykefellkylaqhagrvftraqllhevwgydffggtRtvdvhvRrlraklgpehealigtvRnvgykavrpa > 8hih_Q interface=178,179,181,182,185,186,203, mlelllltselypdpvlpalsllphtvrtapaeasslleagnadavlvdarndlssgrglcrllsstgrsipvlavvsegglvavsadwgldeilllstgpaeidarlrlvvglgkvslgelvidegtytarlrgrpldltykefellkylaqhagrvftraqllhevwgydffggtRTvDVhvRRlraklgpehealigtvRnvgykavrpa
interface signature	RKRAWDERRLER/QKLDRRRAPATA/DVRLILNRLRFFDKYSTYTWWRQRRVHENREIQDEDF/RN/RTDVR/RTDVHRR/RRR/RTDVRRR

Estimated binding specificities ?

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# IC=54.611 IC/col=0.728 n_of_columns=75

specificity:

A |   7   8  24  24  24  24  24  24  24  24  96   0   0   6   0  96   0   0   0   0  96  96   0  96  96  96  24   3  24  96  24  24  24  24   0   0   0   0   2   0   0  24  24  24   0  24  89   2  24  24  24  24  24  24  24   2   0   0   0   0   9  24   0   0  24  24   0   0   0   0   0  89  24  24  82
C |   6   9  24  24  24  24  24  24  24  24   0   0   0  77   0   0   0   0   0   0   0   0   0   0   0   0  24   0  24   0  24  24  24  24   0   0   0   1   3  96   0  24  24  24   0  24   2   3  24  24  24  24  24  24  24   2   0   0   0   0   8  24   0  96  24  24  96  96   0   0   0   2  24  24   6
G |   6  71  24  24  24  24  24  24  24  24   0  96   0   7  96   0  96  96  96   0   0   0   0   0   0   0  24  93  24   0  24  24  24  24  96  96   0   2   2   0  96  24  24  24  96  24   3  89  24  24  24  24  24  24  24   2   0  96   0   0  10  24  96   0  24  24   0   0  96   0  96   2  24  24   4
T |  77   8  24  24  24  24  24  24  24  24   0   0  96   6   0   0   0   0   0  96   0   0  96   0   0   0  24   0  24   0  24  24  24  24   0   0  96  93  89   0   0  24  24  24   0  24   2   2  24  24  24  24  24  24  24  90  96   0  96  96  69  24   0   0  24  24   0   0   0  96   0   3  24  24   4

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updated Thu Sep 12 02:19:15 2024