8scg_AD : 3D-footprint complex

structure name	BST DNA POLYMERASE I LARGE FRAGMENT MUTANT F710Y/D598A WITH 3'-AMINO PRIMER, DGTP, AND CALCIUM TIME-RESOLVED 0H (GROUND STATE)
reference	Lelyveld et al. Science 382 423 2023
source	Geobacillus stearothermophilus
experiment	X-ray (resolution=2.00, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	4yfu_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8scg_A interface=285,289,318,325,328,361,410,413,417,419,420,422,432,496,500,532, kmaftladrvteemladkaalvvevveenyhdapivgiavvnehgrfflrpetaladpqfvawlgdetkkksmfdskraavalkwkgielcgvsfdlllaaylldpaqgvddvaaaakmkqyeavrpdeavygkgakravpdepvlaehlvrkaaaiwelerpfldelrrneqdrllveleqplssilaemefagvkvdtkrleqmgkelaeqlgtveqriyelagqefninspkqlgvilfeklqlpvlkktktgystsadvleklapyheivenilhyrqlgKlqsTyiegllkvvrpatkkvhtifnqaltqtgRlsstepNlqNipirleegrkirqafvpsesdwlifaadysqiElrvlahiaeddnlmeafrrdldihtktamdifqvsedevtpnmrrqakAvnYgivYgISdYglaqnlnisRkeaaefieryfesfpgvkrymenivqeakqkgyvttllhrrrylpditsrnfnvrsfaermamNtpiQgsaadiikkamidlnarlkeerlqahlllqvHdelileapkeemerlcrlvpevmeqavtlrvplkvdyhygstwydak > 8scg_D interface=318,361,410,417,419,420,422,432,496,500, kmaftladrvteemladkaalvvevveenyhdapivgiavvnehgrfflrpetaladpqfvawlgdetkkksmfdskraavalkwkgielcgvsfdlllaaylldpaqgvddvaaaakmkqyeavrpdeavygkgakravpdepvlaehlvrkaaaiwelerpfldelrrneqdrllveleqplssilaemefagvkvdtkrleqmgkelaeqlgtveqriyelagqefninspkqlgvilfeklqlpvlkktktgystsadvleklapyheivenilhyrqlgklqstyiegllkvvrpatkkvhtifnqaltqtgRlsstepnlqnipirleegrkirqafvpsesdwlifaadysqiElrvlahiaeddnlmeafrrdldihtktamdifqvsedevtpnmrrqakAvnygivYgISdYglaqnlnisRkeaaefieryfesfpgvkrymenivqeakqkgyvttllhrrrylpditsrnfnvrsfaermamNtpiQgsaadiikkamidlnarlkeerlqahlllqvhdelileapkeemerlcrlvpevmeqavtlrvplkvdyhygstwydak
interface signature	KTRNNEAYYISYRNQH/REAYISYRNQ

Estimated binding specificities ?

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# IC=6.174 IC/col=0.882 n_of_columns=7

specificity:

A |   6  96   0   9   6   9   0
C |  75   0  96   6  75   6   1
G |   9   0   0  75   6   6  89
T |   6   0   0   6   9  75   6

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updated Thu Jan 8 09:09:44 2026