8scj_AD : 3D-footprint complex

structure name	BST DNA POLYMERASE I LARGE FRAGMENT MUTANT F710Y/D598A WITH 3'-AMINO PRIMER, DGTP, AND CALCIUM TIME-RESOLVED 2H
reference	Lelyveld et al. Science 382 423 2023
source	Geobacillus stearothermophilus
experiment	X-ray (resolution=2.68, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	4yfu_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8scj_A interface=234,235,255,257, kmaftladrvteemladkaalvvevveenyhdapivgiavvnehgrfflrpetaladpqfvawlgdetkkksmfdskraavalkwkgielcgvsfdlllaaylldpaqgvddvaaaakmkqyeavrpdeavygkgakravpdepvlaehlvrkaaaiwelerpfldelrrneqdrllveleqplssilaemefagvkvdtkrleqmgkelaeqlgtveqriyelagqefninsPKqlgvilfeklqlpvlkktkTgYstsadvleklapyheivenilhyrqlgklqstyiegllkvvrpatkkvhtifnqaltqtgrlsstepnlqnipirleegrkirqafvpsesdwlifaadysqielrvlahiaeddnlmeafrrdldihtktamdifqvsedevtpnmrrqakavnygivygisdyglaqnlnisrkeaaefieryfesfpgvkrymenivqeakqkgyvttllhrrrylpditsrnfnvrsfaermamntpiqgsaadiikkamidlnarlkeerlqahlllqvhdelileapkeemerlcrlvpevmeqavtlrvplkvdyhygstwydak > 8scj_D interface=235,255,257,285,289,290,318,328,361,409,413,417,496,500,532, kmaftladrvteemladkaalvvevveenyhdapivgiavvnehgrfflrpetaladpqfvawlgdetkkksmfdskraavalkwkgielcgvsfdlllaaylldpaqgvddvaaaakmkqyeavrpdeavygkgakravpdepvlaehlvrkaaaiwelerpfldelrrneqdrllveleqplssilaemefagvkvdtkrleqmgkelaeqlgtveqriyelagqefninspKqlgvilfeklqlpvlkktkTgYstsadvleklapyheivenilhyrqlgKlqsTYiegllkvvrpatkkvhtifnqaltqtgRlsstepnlqNipirleegrkirqafvpsesdwlifaadysqiElrvlahiaeddnlmeafrrdldihtktamdifqvsedevtpnmrrqaKavnYgivYgisdyglaqnlnisrkeaaefieryfesfpgvkrymenivqeakqkgyvttllhrrrylpditsrnfnvrsfaermamNtpiQgsaadiikkamidlnarlkeerlqahlllqvHdelileapkeemerlcrlvpevmeqavtlrvplkvdyhygstwydak
interface signature	PKTY/KTYKTYRNEKYYNQH

Estimated binding specificities ?

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# IC=5.095 IC/col=0.509 n_of_columns=10

specificity:

A |   0  17   0   0  54  24  24  24  24  96
C |   0  45  10   0  17  24  24  24  24   0
G |  96  17   8  96  17  24  24  24  24   0
T |   0  17  78   0   8  24  24  24  24   0

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updated Thu Sep 12 07:50:35 2024