8scl_AD : 3D-footprint complex

structure name	BST DNA POLYMERASE I LARGE FRAGMENT MUTANT F710Y/D598A WITH 3'-AMINO PRIMER, DGTP, AND CALCIUM TIME-RESOLVED 6H
reference	Lelyveld et al. Science 382 423 2023
source	Geobacillus stearothermophilus
experiment	X-ray (resolution=2.44, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	4yfu_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8scl_A interface=234,235,255,257, kmaftladrvteemladkaalvvevveenyhdapivgiavvnehgrfflrpetaladpqfvawlgdetkkksmfdskraavalkwkgielcgvsfdlllaaylldpaqgvddvaaaakmkqyeavrpdeavygkgakravpdepvlaehlvrkaaaiwelerpfldelrrneqdrllveleqplssilaemefagvkvdtkrleqmgkelaeqlgtveqriyelagqefninsPKqlgvilfeklqlpvlkktkTgYstsadvleklapyheivenilhyrqlgklqstyiegllkvvrpatkkvhtifnqaltqtgrlsstepnlqnipirleegrkirqafvpsesdwlifaadysqielrvlahiaeddnlmeafrrdldihtktamdifqvsedevtpnmrrqakavnygivygisdyglaqnlnisrkeaaefieryfesfpgvkrymenivqeakqkgyvttllhrrrylpditsrnfnvrsfaermamntpiqgsaadiikkamidlnarlkeerlqahlllqvhdelileapkeemerlcrlvpevmeqavtlrvplkvdyhygstwydak > 8scl_D interface=235,255,257,285,289,290,318,328,332,361,406,413,417,496,500,532, kmaftladrvteemladkaalvvevveenyhdapivgiavvnehgrfflrpetaladpqfvawlgdetkkksmfdskraavalkwkgielcgvsfdlllaaylldpaqgvddvaaaakmkqyeavrpdeavygkgakravpdepvlaehlvrkaaaiwelerpfldelrrneqdrllveleqplssilaemefagvkvdtkrleqmgkelaeqlgtveqriyelagqefninspKqlgvilfeklqlpvlkktkTgYstsadvleklapyheivenilhyrqlgKlqsTYiegllkvvrpatkkvhtifnqaltqtgRlsstepnlqNipiRleegrkirqafvpsesdwlifaadysqiElrvlahiaeddnlmeafrrdldihtktamdifqvsedevtpnmrRqakavnYgivYgisdyglaqnlnisrkeaaefieryfesfpgvkrymenivqeakqkgyvttllhrrrylpditsrnfnvrsfaermamNtpiQgsaadiikkamidlnarlkeerlqahlllqvHdelileapkeemerlcrlvpevmeqavtlrvplkvdyhygstwydak
interface signature	PKTY/KTYKTYRNRERYYNQH

Estimated binding specificities ?

contact

# IC=5.807 IC/col=0.581 n_of_columns=10

specificity:

A |   0   0  13   0  54  24  24  24  24  96
C |   0  96  13   0  16  24  24  24  24   0
G |  96   0  13  96  13  24  24  24  24   0
T |   0   0  57   0  13  24  24  24  24   0

scan!

home
updated Fri Aug 1 17:05:18 2025