8sco_AD : 3D-footprint complex

structure name	BST DNA POLYMERASE I LARGE FRAGMENT WILDTYPE D598A WITH 3'-AMINO PRIMER, DGTP, AND CALCIUM TIME-RESOLVED 0H (GROUND STATE)
reference	Lelyveld et al. Science 382 423 2023
source	Geobacillus stearothermophilus
experiment	X-ray (resolution=1.92, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	4yfu_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8sco_A interface=285,289,290,318,325,328,361,410,413,417,419,420,422,432,496,500,532, kmaftladrvteemladkaalvvevveenyhdapivgiavvnehgrfflrpetaladpqfvawlgdetkkksmfdskraavalkwkgielcgvsfdlllaaylldpaqgvddvaaaakmkqyeavrpdeavygkgakravpdepvlaehlvrkaaaiwelerpfldelrrneqdrllveleqplssilaemefagvkvdtkrleqmgkelaeqlgtveqriyelagqefninspkqlgvilfeklqlpvlkktktgystsadvleklapyheivenilhyrqlgKlqsTYiegllkvvrpatkkvhtifnqaltqtgRlsstepNlqNipirleegrkirqafvpsesdwlifaadysqiElrvlahiaeddnlmeafrrdldihtktamdifqvsedevtpnmrrqakAvnFgivYgISdYglaqnlnisRkeaaefieryfesfpgvkrymenivqeakqkgyvttllhrrrylpditsrnfnvrsfaermamNtpiQgsaadiikkamidlnarlkeerlqahlllqvHdelileapkeemerlcrlvpevmeqavtlrvplkvdyhygstwydak > 8sco_D interface=318,361,410,417,419,420,422,432,496,500, kmaftladrvteemladkaalvvevveenyhdapivgiavvnehgrfflrpetaladpqfvawlgdetkkksmfdskraavalkwkgielcgvsfdlllaaylldpaqgvddvaaaakmkqyeavrpdeavygkgakravpdepvlaehlvrkaaaiwelerpfldelrrneqdrllveleqplssilaemefagvkvdtkrleqmgkelaeqlgtveqriyelagqefninspkqlgvilfeklqlpvlkktktgystsadvleklapyheivenilhyrqlgklqstyiegllkvvrpatkkvhtifnqaltqtgRlsstepnlqnipirleegrkirqafvpsesdwlifaadysqiElrvlahiaeddnlmeafrrdldihtktamdifqvsedevtpnmrrqakAvnfgivYgISdYglaqnlnisRkeaaefieryfesfpgvkrymenivqeakqkgyvttllhrrrylpditsrnfnvrsfaermamNtpiQgsaadiikkamidlnarlkeerlqahlllqvhdelileapkeemerlcrlvpevmeqavtlrvplkvdyhygstwydak
interface signature	KTYRNNEAFYISYRNQH/REAYISYRNQ

Estimated binding specificities ?

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# IC=6.080 IC/col=0.869 n_of_columns=7

specificity:

A |   6  96   0   6   6   6   6
C |  78   0  96   6  78   6   6
G |   6   0   0  78   6   6  78
T |   6   0   0   6   6  78   6

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updated Fri Aug 1 17:06:14 2025