8scs_AD : 3D-footprint complex

structure name	BST DNA POLYMERASE I LARGE FRAGMENT WILDTYPE D598A WITH 3'-AMINO PRIMER, DGTP, AND CALCIUM TIME-RESOLVED 8H
reference	Lelyveld et al. Science 382 423 2023
source	Geobacillus stearothermophilus
experiment	X-ray (resolution=2.10, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	4yfu_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8scs_A interface=234,235,255,257, kmaftladrvteemladkaalvvevveenyhdapivgiavvnehgrfflrpetaladpqfvawlgdetkkksmfdskraavalkwkgielcgvsfdlllaaylldpaqgvddvaaaakmkqyeavrpdeavygkgakravpdepvlaehlvrkaaaiwelerpfldelrrneqdrllveleqplssilaemefagvkvdtkrleqmgkelaeqlgtveqriyelagqefninsPKqlgvilfeklqlpvlkktkTgYstsadvleklapyheivenilhyrqlgklqstyiegllkvvrpatkkvhtifnqaltqtgrlsstepnlqnipirleegrkirqafvpsesdwlifaadysqielrvlahiaeddnlmeafrrdldihtktamdifqvsedevtpnmrrqakavnfgivygisdyglaqnlnisrkeaaefieryfesfpgvkrymenivqeakqkgyvttllhrrrylpditsrnfnvrsfaermamntpiqgsaadiikkamidlnarlkeerlqahlllqvhdelileapkeemerlcrlvpevmeqavtlrvplkvdyhygstwydak > 8scs_D interface=234,235,255,257,285,289,290,318,325,328,361,410,413,417,496,500,532, kmaftladrvteemladkaalvvevveenyhdapivgiavvnehgrfflrpetaladpqfvawlgdetkkksmfdskraavalkwkgielcgvsfdlllaaylldpaqgvddvaaaakmkqyeavrpdeavygkgakravpdepvlaehlvrkaaaiwelerpfldelrrneqdrllveleqplssilaemefagvkvdtkrleqmgkelaeqlgtveqriyelagqefninsPKqlgvilfeklqlpvlkktkTgYstsadvleklapyheivenilhyrqlgKlqsTYiegllkvvrpatkkvhtifnqaltqtgRlsstepNlqNipirleegrkirqafvpsesdwlifaadysqiElrvlahiaeddnlmeafrrdldihtktamdifqvsedevtpnmrrqakAvnFgivYgisdyglaqnlnisrkeaaefieryfesfpgvkrymenivqeakqkgyvttllhrrrylpditsrnfnvrsfaermamNtpiQgsaadiikkamidlnarlkeerlqahlllqvHdelileapkeemerlcrlvpevmeqavtlrvplkvdyhygstwydak
interface signature	PKTY/PKTYKTYRNNEAFYNQH

Estimated binding specificities ?

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# IC=5.339 IC/col=0.534 n_of_columns=10

specificity:

A |   0  11  11   0  69  24  24  24  24  96
C |   0  67   9   0   9  24  24  24  24   0
G |  96   9   9  96   9  24  24  24  24   0
T |   0   9  67   0   9  24  24  24  24   0

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updated Thu Sep 12 07:52:57 2024