8sst_D : 3D-footprint complex

structure name	ZNFS 1-7 OF CCCTC-BINDING FACTOR (CTCF) K365T MUTANT COMPLEXED WITH 23MER (Transcriptional repressor CTCF)
reference	Horton et al. 'Nucleic 51 8447 2023
source	Homo sapiens
experiment	X-ray (resolution=2.19, R-factor=0.221)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
reference complex	5kkq_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8sst_D interface=13,16,19,44,69,70,72,75,79,98,104,126,128,129,132,154,157,184,186,187,190, tfqcelcsytcpRrsNldRhmkshtderphkchlcgrafrtvtLlrnhlnthtgtrphkcpdcdmafvTSgElvRhrrYkhthekpfkcsmcdyasvEvstlkRhirshtgerpfqcslcsyasrDtYKlkRhmrthsgekpyecyicharftQsgTmkmhilqkhtenvakfhcphcdtviaRkSDlgVhlrkqhsy
interface signature	RNRLTSERYERDYKRQTRSDV

Estimated binding specificities ?

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# IC=19.485 IC/col=1.026 n_of_columns=19

specificity:

A |   0  96  24  24  81   5   0   0   5   0   0   0   0   0   6   5   0   0   5
C |  96   0  24  24   5   5  96   0  79  96  96  96  96   0   0  81   0   0   5
G |   0   0  24  24   5  81   0  96   7   0   0   0   0   0  90   5   0  96  79
T |   0   0  24  24   5   5   0   0   5   0   0   0   0  96   0   5  96   0   7

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updated Fri Sep 13 13:34:08 2024