interface graph thumbnail
legend  pdf

structure nameZNFS 3-11 OF CCCTC-BINDING FACTOR (CTCF) COMPLEXED WITH 19MER DNA
referenceHorton et al. 'Nucleic 51 8447 2023
experimentX-ray (resolution=2.89, R-factor=0.202)
structural superfamilybeta-beta-alpha zinc fingers;
sequence familyZinc finger, C2H2 type;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTERYESKRDYKRQTRSDV

Estimated binding specificities ?

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# IC=16.554 IC/col=1.104 n_of_columns=15 specificity:   
A |  11   0  79   5   5  96   0   0   5   0   0   0   0   0  79
C |  73  96   5   5  79   0   0   0   0   0   0  96   0  96   5
G |   5   0   7  81   5   0  96  96  90  96  96   0  96   0   5
T |   7   0   5   5   7   0   0   0   1   0   0   0   0   0   7
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updated Mon Aug 4 02:13:27 2025