8to6_IJLM : 3D-footprint complex

structure name	ESCHERICHIA COLI RNA POLYMERASE UNWINDING INTERMEDIATE (I1D) AT THE LAMBDA PR PROMOTER
experiment	NMR
structural superfamily	Insert subdomain of RNA polymerase alpha subunit;C-terminal domain of RNA polymerase alpha subunit;RBP11-like subunits of RNA polymerase;
reference complex	3iyd_A 7c97_K 8y6u_I
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8to6_I interface=369,370, vysytekkrirkdfgkrpqvldvpyllsiqldsfqkfieqdpegqygleaafrsvfpiqsysgnselqyvsyrlgepvfdvqecqirgvtysaplrvklrlviyereapegtvkdikeqevymgeiplmtdngtfvingtervivsqlhrspgvffdsdkgkthssgkvlynariipyrgswldfefdpkdnlfvridrrrklpatiilralnytteqildlffekvifeiklqmelvperlrgtasfdieangkvyvekgrritarhirqlekddvklievpveyiagkvvakdyidestgelicaanmelsldllaklsqsghkrietlftndldhgpyisetlrvdptndrlsalveiyrmmrpgEPptreaaeslfenlffsedrydlsavgrmkfnrsllreeiegsgilskddiidvmkklidirngkgevddidhlgnrrirsvgemaenqfrvglvrveravkerlslgdldtlmpqdminakpisaavkeffgssqlsqfmdqnnplseithkrrisalgpggltreragfevrdvhpthygrvcpietpegpniglinslsvyaqtneygfletpyrkvtdgvvtdeihylsaieegnyviaqansnldeeghfvedlvtcrskgesslfsrdqvdymdvstqqvvsvgaslipflehddanralmganmqrqavptlradkplvgtgmeravavdsgvtavakrggvvqyvdasrivikvnedemypgeagidiynltkytrsnqntcinqmpcvslgepvergdvladgpstdlgelalgqnmrvafmpwngynfedsilvservvqedrfttihiqelacvsrdtklgpeeitadipnvgeaalskldesgivyigaevtggdilvgkvtpkgetqltpeekllraifgekasdvkdsslrvpngvsgtvidvqvftrdgvekdkraleieemqlkqakkdlseelqileaglfsriravlvaggveaekldklprdrwlelgltdeekqnqleqlaeqydelkhefekkleakrrkitqgddlapgvlkivkvylavkrriqpgdkmagrhgnkgviskinpiedmpydengtpvdivlnplgvpsrmnigqilethlgmaakgigdkinamlkqqqevaklrefiqraydlgadvrqkvdlstfsdeevmrlaenlrkgmpiatpvfdgakeaeikellklgdlptsgqirlydgrtgeqferpvtvgymymlklnhlvddkmharstgsyslvtqqplggkaqfggqrfgemevwaleaygaaytlqemltvksddvngrtkmyknivdgnhqmepgmpesfnvllkeirslginieled > 8to6_J interface= efdaikialaspdmirswsfgevkkpetinyrtfkperdglfcarifgpvkdyeclcgkykrlkhrgvicekcgvevtqtkvrrermghielasptahiwflkslpsrigllldmplrdiervlyfesyvvieggmtnlerqqilteeqyldaleefgdefdakmgaeaiqallksmdleqeceqlreelnetnsetkrkkltkriklleafvqsgnkpewmiltvlpvlppdlrplvpldggrfatsdlndlyrrvinrnnrlkrlldlaapdiivrnekrmlqeavdalldngrrgraitgsnkrplksladmikgkqgrfrqnllgkrvdysgrsvitvgpylrlhqcglpkkmalelfkpfiygKLelrglattikaakkmvereeavvwdildevirehpvllnraptlhrlgiqafepvliegkaiqlhplvcaaynadfdgdqmavhvpltleaqlearalmmstnnilspangepiivpsqdvvlglyymtrdcvnakgegmvltgpkeaerlyrsglaslharvkvriteyekdangelvaktslkdttvgrailwmivpkglpysivnqalgkkaiskmlntcyrilglkptvifadqimytgfayaarsgasvgiddmvipekkheiiseaeaevaeiqeqfqsglvtagerynkvidiwaaandrvskammdnlqtetvinrdgqeekqvsfnsiymmadsgargsaaqirqlagmrglmakpdgsiietpitanfreglnvlqyfisthgarkgladtalktansgyltrrlvdvaqdlvvteddcgthegimmtpvieggdvkeplrdrvlgrvtaedvlkpgtadilvprntllheqwcdlleensvdavkvrsvvscdtdfgvcahcygrdlarghiinkgeaigviaaqsigepgtqlssiqvknkgsiklsnvksvvnssgklvitsrntelklidefgrtkesykvpygavlakgdgeqvaggetvanwdphtmpvitevsgfvrftdmidgqtitrqtdeltglsslvvldsaertaggkdlrpalkivdaqgndvlipgtdmpaqyflpgkaivqledgvqissgdtlaripqtgglprvadlfearrpkepailaeisgivsfgketkgkrrlvitpvdgsdpyeemipkwrqlnvfegervergdvisdgpeaphdilrlrgvhavtryivnevqdvyrlqgvkindkhievivrqmlrkativnagssdflegeqveysrvkianreleangkvgatysrdllgitkaslatesfisaasfqettrvlteaavagkrdelrglkenvivgrlipagtgyayhqdrmrrraa > 8to6_L interface=9,17,243,244,277,278,281,283,284,286,287,288,290,291,292,295,313,442,443,444,446,447, ttdpvrmyMremgtveLltregeidiakriedginqvqcsvaeypeaitylleqydrveaeearlsdlitgfvdidpelarekfaelraqyvvtrdtikhataqeeilklsevfkqfrlvpkqfdylvnsmrvmmdrvrtqerlimklcveqckmpkknfitlftgnetsdtwfnaaiamnkpwseklhdvseevhralqklqqieeetgltieqvkdinrrmsigeakarrakkemveanlRLvisiakkytnrglqfldliqegniglmkavdkFEyrRgYKfSTYaTWWirQaitrsiadqartiripvHmietinklnrisrqmlqemgreptpeelaermlmpedkirkvlkiakepismetpigddedshlgdfiedttlelpldsatteslraathdvlagltareakvlrmrfgidmntdytleevgkqfdvtRERiRQieakalrklrhpsrsevlrsfld > 8to6_M interface= dpillrpvDdleltvrSanclkaeaihyigdlvqrtevellktpnlgkkslteikdvlasrglslgmrlenwp
interface signature	EP/KL/MLRLFERYKSTYTWWQHRERRQ/DS

Estimated binding specificities ?

readout + contact

# IC=9.381 IC/col=0.313 n_of_columns=30

specificity:

A |   0   0  65  24  24  96  24  96  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  50   0   0  24  66  66
C |  96   0  11  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  15   0   0  24  10  10
G |   0   0  10  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  15  96   0  24  10  10
T |   0  96  10  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  16   0  96  24  10  10

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updated Mon Dec 16 11:30:02 2024