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structure nameCRYSTAL STRUCTURE OF HUMAN POLYMERASE ETA WITH INCOMING DGMPNPP NUCLEOTIDE OPPOSITE UREA LESION
(DNA polymerase eta)
referenceStone et al. Biochemistry 63 754 2024
sourceHomo sapiens
experimentX-ray (resolution=2.17, R-factor=0.174)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSNLRMF

Estimated binding specificities ?

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# IC=3.101 IC/col=0.517 n_of_columns=6 specificity:   
A |   0  13  24  24  96  13
C |  96  13  24  24   0  13
G |   0  54  24  24   0  16
T |   0  16  24  24   0  54
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updated Fri Sep 13 14:02:41 2024