8wpf_AEG : 3D-footprint complex

structure name	STRUCTURE OF MONKEYPOX VIRUS POLYMERASE COMPLEX F8-A22-E4-H5 WITH EXOGENOUS DNA BEARING ONE ABASIC SITE
experiment	NMR
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;Uracil-DNA glycosylase-like;
reference complex	8hg1_A 8hg1_B 8hg1_C 8wpe_G
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8wpf_A interface=668,804,832, mdvrcinwfeshgenrflylksrcrngetvfirfphyfyyvvtdeiyqslspppfnarpmgkmrtididetisynldikdrkcsvadmwlieepkkrsiqnatmdeffniswfyisngispdgcysldeqyltkinngcyhcddprncfakeiprfdiprsylfldiechfdkkfpsvfinpishtsycyidlsgkrllftlineemlteqeiqeavdrgclriqslmemdyerelvlcseivllriakqlleltfdyvvtfnghnfdlryitnrlelltgekiifrspdkkeavhlciyernqsshkgvcgmanttfhvnnnngtiffdlysfiqksekldsykldsisknafscmgkvlnrgvremtfigddttdakgkadtfakvlttgnyvtvdediickvirkdilengfkvvlscptlpndiyklsfgkddidlaqmykdynlnialdmarycihdaclcqylweyygvetktdagaatyvlpqsmvfeyrastiikgpllkllletktilvrsetkqkfpyeggkvfapkqkmfsnnvlifdynslypnvcifgnlspetlvgvvvstnrleeeinnqlllqkypppryitvhceprlpnliseiaifdrsiegtiprllrtflaerarykkmlkqatsstekaiydsmqytykivansvYglmgfrnsalysyasaksctsigrrmilylesvlngaelsngmlrfantlsnpfymddrdinpivktslpidyrfrfrsvygdtdsvfteidsqdvdksieiakelerlinsrvlfnnfkiefeavyknlimqskKkyttmkysassnsksvperinkgtsetRrdvskfhknmiktyktrlsemlsegrmnsnqvcidilrsletdlrsefdsrssplelfmlsrmhhsnyksadnpnmylvteynknnpetielgeryyfayicpanvpwtkklvniktyetiidrsfklgsnqrifyevyfkrltseivnlldnkvlcisffqrmfgsrptfyea > 8wpf_E interface=38, sdlkvatdnivkdlkkiitrisavstvledvqaagisRqftsmtkaittlsdlvteg > 8wpf_G interface=38, sdlkvatdnivkdlkkiitrisavstvledvqaagisRqftsmtkaittlsdlvteg
interface signature	YKR/R/R

Estimated binding specificities ?

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# IC=7.016 IC/col=0.251 n_of_columns=28

specificity:

A |   4   4  84  82   6  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   4  96  24  24  24  24  24   4
C |   6  82   4   6   4  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   4   0  24  24  24  24  24  82
G |  82   4   4   4   4  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   4   0  24  24  24  24  24   6
T |   4   6   4   4  82  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  84   0  24  24  24  24  24   4

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updated Thu Jan 8 15:22:44 2026