8x1z_AB : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE MUTANT Q151M/Y115F/F116Y:DNA:E-CFCP-TP TERNARY COMPLEX
reference	Hattori et al. 'Sci 14 15742 2024
experiment	X-ray (resolution=2.62, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8x1z_A interface=24,25,61,63,74,78,94,157,183,184,448, pispietvpvklkpgmdgpkvkqWPlteekikalveictemekegkiskigpenpyntpvFaIkkkdstkwrkLvdfRelnkrtqdfwevqlgIphpaglkqkksvtvldvgdafysvpldkdfrkytaftipsinnetpgiryqynvlpmgwkgsPaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanRetklgkagyvtdrgrqkvvpltdttnqktelqaihlalqdsglevnivtdsqyalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 8x1z_B interface=245,248,325, ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkqkksvtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnWasQiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepFknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WPFILRIPYMR/WQF

Estimated binding specificities ?

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# IC=8.431 IC/col=0.263 n_of_columns=32

specificity:

A |   0   0  16   0  24  24  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24  13   0
C |   0  96  13  96  24  24  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24  13   0
G |   0   0  54   0  24  24  24  24  24  24  24  24  24  24  24   0  24   0  24  24  24  24  24  24  24  24  24  24  24  24  54  96
T |  96   0  13   0  24  24  24  24  24  24  24  24  24  24  24  96  24  96  24  24  24  24  24  24  24  24  24  24  24  24  16   0

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updated Thu Jan 8 15:33:07 2026