8x1z_CD : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE MUTANT Q151M/Y115F/F116Y:DNA:E-CFCP-TP TERNARY COMPLEX
reference	Hattori et al. 'Sci 14 15742 2024
experiment	X-ray (resolution=2.62, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8x1z_C interface=24,61,63,74,76,78,94,157,183,184,448,475,501, pispietvpvklkpgmdgpkvkqWplteekikalveictemekegkiskigpenpyntpvFaIkkkdstkwrkLvDfRelnkrtqdfwevqlgIphpaglkqkksvtvldvgdafysvpldkdfrkytaftipsinnetpgiryqynvlpmgwkgsPaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanRetklgkagyvtdrgrqkvvpltdttnQktelqaihlalqdsglevnivtdsqYalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 8x1z_D interface= ietvpvklkpgmdgpkvkqwpltEekikalveictemekegkiskigpenpyntpvfaikKkDstkwrklvdfReLnKrtqdfwevqlgiphpAglkqkksvtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkgspaifQssmtkilepfrkqnpdiviyqymddLYvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WFILDRIPYMRQY/EKDRLKAQLY

Estimated binding specificities ?

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# IC=9.740 IC/col=0.295 n_of_columns=33

specificity:

A |   0   0   5   0  24  24  24  24  24  24  24  24  24  24  24   5  24  11   0  24  24  24  24  24  24  24  24  24  24  24   5   0  11
C |   0  96   2  96  24  24  24  24  24  24  24  24  24  24  24   5  24   5   0  24  24  24  24  24  24  24  24  24  24  24   7   0  62
G |   0   0  84   0  24  24  24  24  24  24  24  24  24  24  24   7  24  13  96  24  24  24  24  24  24  24  24  24  24  24  79  96  11
T |  96   0   5   0  24  24  24  24  24  24  24  24  24  24  24  79  24  67   0  24  24  24  24  24  24  24  24  24  24  24   5   0  12

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updated Thu Jan 8 15:33:39 2026