8x20_CD : 3D-footprint complex

structure name	HIV-1 REVERSE TRANSCRIPTASE MUTANT Q151M/Y115F/F116Y/L74V:DNA:E-CFCP- TP TERNARY COMPLEX
reference	Hattori et al. 'Sci 14 15742 2024
experiment	X-ray (resolution=2.70, R-factor=?)
structural superfamily	DNA/RNA polymerases;Ribonuclease H-like;
reference complex	7ozw_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 8x20_C interface=24,61,74,76,78,94,157,183,184,265,475,501, pispietvpvklkpgmdgpkvkqWplteekikalveictemekegkiskigpenpyntpvFaikkkdstkwrkVvDfRelnkrtqdfwevqlgIphpaglkqkksvtvldvgdafysvpldkdfrkytaftipsinnetpgiryqynvlpmgwkgsPaifqssmtkilepfrkqnpdiviyqYMddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklNwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwyqlekepiigaetfyvdgaanretklgkagyvtdrgrqkvvpltdttnQktelqaihlalqdsglevnivtdsqYalgiiqaqpdkseselvsqiieqlikkekvylawvpahkgiggneqvdklvs > 8x20_D interface= ietvpvklkpgmdgpkvkqwpltEekikalveictemekegkiskigpenpyntpvfaikKkdstkwrklvdfReLnKrtqdfwevqlgiphpAglkqkksvtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkgspaifQssmtkilepfrkqnpdiviyqymddLYvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgTkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy
interface signature	WFVDRIPYMNQY/EKRLKAQLYT

Estimated binding specificities ?

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# IC=8.745 IC/col=0.265 n_of_columns=33

specificity:

A |   0   0   6   6  24  24  24  24  24  24  24  24  24  24  24   6  24  24   0  24  24  24  24  24  24  24  24  24  24  24   6   0   6
C |   0  96   6  78  24  24  24  24  24  24  24  24  24  24  24   6  24  24   0  24  24  24  24  24  24  24  24  24  24  24   6   0  78
G |   0   0  78   6  24  24  24  24  24  24  24  24  24  24  24   6  24  24  96  24  24  24  24  24  24  24  24  24  24  24  78  96   6
T |  96   0   6   6  24  24  24  24  24  24  24  24  24  24  24  78  24  24   0  24  24  24  24  24  24  24  24  24  24  24   6   0   6

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updated Thu Jan 8 15:34:47 2026