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structure nameDETERMINATION OF THE NMR SOLUTION STRUCTURE OF AN ANTENNAPEDIA HOMEODOMAIN-DNA COMPLEX
(HOMEOTIC PROTEIN ANTENNAPEDIA)
sourceDROSOPHILA SUBOBSCURA
experimentNMR
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRRKIQNM

Estimated binding specificities ?

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# IC=7.252 IC/col=0.659 n_of_columns=11 specificity:   
A |  81  24  24  24   0  84   4   9  67   0  88
C |   4  24  24  24  96   4   4   0  14   0   0
G |   7  24  24  24   0   4   4  15   4  96   4
T |   4  24  24  24   0   4  84  72  11   0   4
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --RA--------IT----QTNA--MG----   L                              +5zjt_E    
                                          +-----------------------1 
  RCRT--------NT------NA--IT----   L      !                       +5zjt_B    
                                          !  
  --RT------KTIA----QCNA------RT   L      !                       +1ig7_A    
                                          !                     +-3 
  --RT--------NT------NA--IARG--   L      !              +------6 +1b72_B    
                                       +-10              !      ! 
  ------------NC----ITNA--RGRG--   L   !  !    +---------7      +-6fqq_E    
                                       !  !    !         ! 
  ------------IA------NA--------       !  !    !         !       +4qtr_D    
                                       !  !    !         +-------4 
  --RT--------IT----QCNA--ACRG--   L   !  !    !                 +6a8r_A    
                                       !  +----9 
  --RT--------IA----KGNA--------   L -11       !                   +2hdd_A    
                                       !       !                 +-2 
  --RT--------NT------NA----RG--   L   !       !       +---------5 +1b8i_B    
                                       !       !       !         ! 
  ------YTVC----KGDC----KC------   L   !       +-------8         +2qhb_A    
                                       !               ! 
  --RA------KGSA----QA----------   L   !               +----------6j5b_C    
                                       !  
  --RAYA------IA----QCNA--YCKG--   L   +--------------------------5flv_I    
                                     

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updated Mon Dec 16 17:38:54 2024