5jlw_D : 3D-footprint complex

structure name	ANTPHD WITH 15BP DNA DUPLEX R-MONOTHIOATED AT CYTIDINE-8 (Homeotic protein antennapedia)
reference	Zandarashvili et al. Chembiochem 17 1636 2016
source	Drosophila melanogaster
experiment	X-ray (resolution=2.09, R-factor=0.219)
structural superfamily	Homeodomain-like;
sequence family	Homeobox domain;
redundant complexes	1ahd_P 4xic_D 4xid_D 5jlx_D 9ant_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5jlw_D interface=2,40,44,47,48, gRqtytryqtlelekefhfnryltrrrrieiahalslteRqikIwfQNrrmkwkken
interface signature	RRIQN

Estimated binding specificities ?

contact

# IC=5.379 IC/col=0.896 n_of_columns=6

specificity:

A |   9  67   0   0  69   0
C |  69   9   0   0   9   0
G |   9   9   0   0   9  96
T |   9  11  96  96   9   0

scan!

Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: ANTENNAPEDIA
TAATG	PubMed	5jlw_D(1.20e-07), 4xic_A(3.59e-04), 4xid_D(7.10e-07), ... (total=5)
CCAAT	PubMed	5jlw_D(2.85e-03), 4xic_A(2.64e-03), 4xid_D(6.05e-03), ... (total=5)
TTAATT	PubMed	5jlw_D(1.12e-03), 4xic_A(1.13e-03), 4xid_D(3.38e-03), ... (total=5)

Dendrogram of similar interfaces ?

matrix format

  
  --RT----------NT--NAIARG   L                           +4cyc_B    
                                        +----------------1 
  --------------NCITNARGRG   L     +----2                +6fqq_E    
                                   !    ! 
  RT------------VTQTNA--RG   L   +-3    +----------------8ejp_B    
                                 ! ! 
  ----------STTAQCST------     --4 +---------------------8b4b_W    
                                 ! 
  ----STRGQTQAST----------   L   +-----------------------7t8k_B

home
updated Mon Jun 29 20:16:40 2026