interface graph thumbnail
legend  pdf

structure namePBX1, HOMEOBOX PROTEIN HOX-B1/DNA TERNARY COMPLEX
(PROTEIN PBX1)
referenceBatchelor et al. 'Cell(Cambridge,Mass.)' 96 587 1999
sourceHOMO SAPIENS
experimentX-ray (resolution=2.35, R-factor=0.243)
structural superfamilyHomeodomain-like;
sequence familyHomeobox domain;
multimeric complexes1b72_AB
redundant complexes1lfu_P
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNNIR

Estimated binding specificities ?

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# IC=4.434 IC/col=0.887 n_of_columns=5 specificity:   
A |  54   0   0  96  13
C |  13   0  96   0  13
G |  16   0   0   0  16
T |  13  96   0   0  54
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RT--------------------NT--NAIARG--------   L                        +1b72_B    
                                                                  +---3 
  RT--------------------NT--NAITRG--------   L           +--------6   +5zjt_B    
                                                         !        ! 
  RA--------------------ITQTNAMG----------   L       +---8        +----5zjt_E    
                                                     !   ! 
  ----------------------IA--NA------------       +--12   +-------------4qtr_D    
                                                 !   !  
  ----------------------NCITNA--------RGRG   L   !   !             +---6fqq_E    
                                                 !   +-------------5 
  ----------NT----------------------------       !                 +---7tve_F    
                                                 !  
  RT--------------------NT--NA--RG--------   L   !                      +1b8i_B    
                                                 !              +-------4 
  RA------------------KGSAQA--------------   L   !              !       +6j5b_C    
                                               -14        +-----7 
  RT------------------KTIAQCNA----RT------   L   !        !     !        +1ig7_A    
                                                 !        !     +--------2 
  RT--------------------ITQCNAACRG--------   L   !     +-10              +6a8r_A    
                                                 !     !  !  
  RT--------------------IAKGNA------------   L   !     !  !                +2hdd_A    
                                                 !     !  ! +--------------1 
  --------------YTVC--KGDCKC--------------   L   !  +-11  +-9              +2qhb_A    
                                                 !  !  !    ! 
  RA------YA------------IAQCNAYCKG--------   L   !  !  !    +--------------5flv_I    
                                                 +-13  !  
  ----------------RTQT--ITQANA------VTKT--   L      !  +----------------2ld5_A    
                                                    !  
  --NGRGTG----LG--LCRG--------------------          +------------------4e9f_A    
                                               

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updated Thu Dec 22 17:21:58 2022