1c0w_ABCD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE COBALT-ACTIVATED DIPHTHERIA TOXIN REPRESSOR- DNA COMPLEX REVEALS A METAL BINDING SH-LIKE DOMAIN
reference	Holmes et al. J.Mol.Biol. 292 653 1999
source	Corynebacterium diphtheriae
experiment	X-ray (resolution=3.20, R-factor=?)
structural superfamily	Iron-dependent repressor protein, dimerization domain;"Winged helix" DNA-binding domain;
reference complex	1ddn_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1c0w_A interface=36,38,39,42,46, kdlvdttemylrtiyeleeegvtplrariaerleqSgPTvsQtvaRmerdglvvvasdrslqmtptgrtlatavmrkhrlaerlltdiigldinkvhdeacrwehvmsdeverrlvkvlkdvsrspfgnpipgldelgvivqineifqvetdqftqlldavellddlahtiri > 1c0w_B interface=36,38,39,41,42, kdlvdttemylrtiyeleeegvtplrariaerleqSgPTvSQtvarmerdglvvvasdrslqmtptgrtlatavmrkhrlaerlltdiigldinkvhdeacrwehvmsdeverrlvkvlkdvsrspfgnpipgldelgvapgtrvidaatsmprkvrivqineifqvetdqftqlldadirvgseveivdrdghitlshngkdvellddlahtirieel > 1c0w_C interface=36,38,39,42,46, kdlvdttemylrtiyeleeegvtplrariaerleqSgPTvsQtvaRmerdglvvvasdrslqmtptgrtlatavmrkhrlaerlltdiigldinkvhdeacrwehvmsdeverrlvkvlkdvsrspfgnpipgldelgvivqineifqvetdqftqlldadirvellddlahtir > 1c0w_D interface=36,38,39,41,42, kdlvdttemylrtiyeleeegvtplrariaerleqSgPTvSQtvarmerdglvvvasdrslqmtptgrtlatavmrkhrlaerlltdiigldinkvhdeacrwehvmsdeverrlvkvlkdvsrspfgnpipgldelgvvqineifqvetdqftqlldadirvvellddlahtir
interface signature	SPTQR/SPTSQ/SPTQR/SPTSQ

Estimated binding specificities ?

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# IC=15.003 IC/col=1.000 n_of_columns=15

specificity:

A |  16  24  75   5   0   0  96   0   0   0   0  96   0  10   6
C |   5  24   5   6   0   0   0   1  96  96   0   0  96  75   5
G |   5  24   5  80  96   0   0  90   0   0   0   0   0   5   5
T |  70  24  11   5   0  96   0   5   0   0  96   0   0   6  80

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updated Tue Jul 29 14:25:43 2025