interface graph thumbnail
legend  pdf

structure nameDIPHTHERIA TOX REPRESSOR (C102D MUTANT)/TOX DNA OPERATOR COMPLEX
(DIPHTHERIA TOX REPRESSOR)
referenceVanderspek et al.
sourceCorynebacterium diphtheriae
experimentX-ray (resolution=3.00, R-factor=?)
structural superfamilyIron-dependent repressor protein, dimerization domain;"Winged helix" DNA-binding domain;
sequence familyIron dependent repressor, Nterminal D; Iron dependent repressor, metal bindin; MarR family;
multimeric complexes1c0w_ABCD 1ddn_ABCD 1f5t_ABCD
redundant complexes1c0w_D 1f5t_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSPTSQR

Estimated binding specificities ?

readout + contactlogo
# IC=4.960 IC/col=0.827 n_of_columns=6 specificity:   
A |  73   0   9   0  75  73
C |   9  96  73   0   7   7
G |   7   0   7   0   7   7
T |   7   0   7  96   7   9
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: TOX REPRESSOR
ACAATTAGGPubMed1ddn_B(3.90e-05), 1c0w_D(3.90e-06)
ATAATTAGGPubMed1ddn_B(3.90e-05), 1c0w_D(3.90e-06)

Dendrogram of similar interfaces ?

matrix format
  
  ----RGSTRTSTHG------------   L                          +3zpl_B    
                                          +---------------1 
  ------------RCYG----KT----          +---2               +2acj_B    
                                      !   ! 
  --------------YG----------       +--3   +----------------3eyi_B    
                                   !  ! 
  --DCLT--AGTTRG--RG--------   L --4  +--------------------5h3r_A    
                                   ! 
  TT----KATTQTTGLTRTKA--FTYT   L   +-----------------------2p7c_B

home
updated Sat Jan 10 04:32:40 2026