3D-footprint cannot reliably estimate the specificity of histones, as they display few contacts over long stretches of DNA.


Dendrogram of similar interfaces ?

matrix format
structure nameX-RAY STRUCTURE OF THE NUCLEOSOME CORE PARTICLE AT 2.5 A RESOLUTION
(PROTEIN HISTONE H2A)
referenceHanson et al.
sourceGALLUS GALLUS
experimentX-ray (resolution=2.50, R-factor=0.219)
structural superfamilyHistone-fold;
sequence familyCore histone H2A/H2B/H3/H4;
multimeric complexes1eqz_ABCDEFGH 6nzo_ABCDEFGHS 6px1_ABCDEFGH 6px3_ABCDEFGHS
reference complex6px1_C
links to other resourcesNAKB PDBSum PDIdb DNAproDB 
  
  --KT------RT--   L                 +2f8n_G    
                                   +-1 
  KT--------RA--       +-----------3 +1kx5_G    
                       !           ! 
  ------------RA       !           +2cv5_G    
                       ! 
  ----------RC--       !       +----1kx5_B    
                     --8    +--5 
  ------PT------       !    !  +----1id3_F    
                       !  +-6 
  ------LT--RA--       !  ! !       +1id3_A    
                       !  ! +-------2 
  ------LT--RC--       +--7         +1kx5_E    
                          ! 
  ----------KG--          !        +1jfi_A    
                          +--------4 
  ----RAAANA----                   +1jfi_B

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updated Thu Jan 8 17:52:52 2026