1f5t_ABCD : 3D-footprint complex

structure name	DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL AND DTXR CONSENSUS BINDING SEQUENCE
reference	Murphy et al. Biochemistry 39 10397 2000
source	Corynebacterium diphtheriae
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;Iron-dependent repressor protein, dimerization domain;
reference complex	1f5t_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1f5t_A interface=36,38,39,42,46, kdlvdttemylrtiyeleeegvtplrariaerleqSgPTvsQtvaRmerdglvvvasdrslqmtptgrtlatavmrkhrlaerlltdiigldinkvhdeadrwehvmsdeverrlvkvlk > 1f5t_B interface=1,36,38,39,41,42,46, KdlvdttemylrtiyeleeegvtplrariaerleqSgPTvSQtvaRmerdglvvvasdrslqmtptgrtlatavmrkhrlaerlltdiigldinkvhdeadrwehvmsdeverrlvkvlk > 1f5t_C interface=36,38,39,41,42,46, kdlvdttemylrtiyeleeegvtplrariaerleqSgPTvSQtvaRmerdglvvvasdrslqmtptgrtlatavmrkhrlaerlltdiigldinkvhdeadrwehvmsdeverrlvkvlk > 1f5t_D interface=1,36,38,39,41,42,46, KdlvdttemylrtiyeleeegvtplrariaerleqSgPTvSQtvaRmerdglvvvasdrslqmtptgrtlatavmrkhrlaerlltdiigldinkvhdeadrwehvmsdeverrlvkvlk
interface signature	SPTQR/KSPTSQR/SPTSQR/KSPTSQR

Estimated binding specificities ?

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# IC=15.599 IC/col=1.040 n_of_columns=15

specificity:

A |  96   8   0   0   8  96   0   0   0   0  48  96   0  24   0
C |   0   8   0   0  16   0   0  96  96   0  16   0  96  24   0
G |   0  72  96   0  16   0  96   0   0   0  16   0   0  24   0
T |   0   8   0  96  56   0   0   0   0  96  16   0   0  24  96

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updated Tue Jul 29 14:42:15 2025