1f5t_ABCD : 3D-footprint complex

structure name	DIPHTHERIA TOX REPRESSOR (C102D MUTANT) COMPLEXED WITH NICKEL AND DTXR CONSENSUS BINDING SEQUENCE
reference	Murphy et al. Biochemistry 39 10397 2000
source	Corynebacterium diphtheriae
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	Iron-dependent repressor protein, dimerization domain;"Winged helix" DNA-binding domain;
reference complex	1ddn_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1f5t_A interface=36,38,39,42,46, kdlvdttemylrtiyeleeegvtplrariaerleqSgPTvsQtvaRmerdglvvvasdrslqmtptgrtlatavmrkhrlaerlltdiigldinkvhdeadrwehvmsdeverrlvkvlk > 1f5t_B interface=1,36,38,39,41,42,46, KdlvdttemylrtiyeleeegvtplrariaerleqSgPTvSQtvaRmerdglvvvasdrslqmtptgrtlatavmrkhrlaerlltdiigldinkvhdeadrwehvmsdeverrlvkvlk > 1f5t_C interface=36,38,39,41,42,46, kdlvdttemylrtiyeleeegvtplrariaerleqSgPTvSQtvaRmerdglvvvasdrslqmtptgrtlatavmrkhrlaerlltdiigldinkvhdeadrwehvmsdeverrlvkvlk > 1f5t_D interface=1,36,38,39,41,42,46, KdlvdttemylrtiyeleeegvtplrariaerleqSgPTvSQtvaRmerdglvvvasdrslqmtptgrtlatavmrkhrlaerlltdiigldinkvhdeadrwehvmsdeverrlvkvlk
interface signature	SPTQR/KSPTSQR/SPTSQR/KSPTSQR

Estimated binding specificities ?

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# IC=15.599 IC/col=1.040 n_of_columns=15

specificity:

A |  96  24   0   0  16  96   0   0   0   0  56  96   0   8   0
C |   0  24   0   0  16   0   0   0  96   0  16   0  96  72   0
G |   0  24  96   0  16   0  96  96   0   0   8   0   0   8   0
T |   0  24   0  96  48   0   0   0   0  96  16   0   0   8  96

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updated Sun Jan 4 21:10:01 2026