1ga5_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA- BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT
reference	Rastinejad et al.
source	Homo sapiens
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1a6y_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1ga5_A interface=22,25,29,30,77,79, vllckvcgdvasgfhygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrFgRipk > 1ga5_B interface=15,22,25,29,30,77, vllckvcgdvasgfHygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrFgr
interface signature	EKRRFR/HEKRRF

Estimated binding specificities ?

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# IC=12.332 IC/col=0.725 n_of_columns=17

specificity:

A |   4   0   4   0   0  24  24  24   4   0  86   4   0   9  24  24   4
C |   7   0  81  96  96  24  24  24   4   0   6  91  96   9  24  24   4
G |   4  96   7   0   0  24  24  24   4  96   0   1   0   6  24  24  12
T |  81   0   4   0   0  24  24  24  84   0   4   0   0  72  24  24  76

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updated Tue Jul 29 14:48:32 2025