1ga5_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA- BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT
reference	Rastinejad et al.
source	Homo sapiens
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1a6y_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1ga5_A interface=22,25,29,30,77,79, vllckvcgdvasgfhygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrFgRipk > 1ga5_B interface=15,22,25,29,30,77, vllckvcgdvasgfHygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrFgr
interface signature	EKRRFR/HEKRRF

Estimated binding specificities ?

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# IC=13.593 IC/col=0.800 n_of_columns=17

specificity:

A |  81  24  24  69   0   0   0   0  81  11  24  24   0   0   1   0  81
C |   7  24  24   9   0   1   0  96   7  76  24  24   0   0   0  96   7
G |   4  24  24   9  96  91   0   0   4   0  24  24  96  96  86   0   4
T |   4  24  24   9   0   4  96   0   4   9  24  24   0   0   9   0   4

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updated Sun Jan 4 21:17:08 2026