1a6y_A : 3D-footprint complex

structure name	REVERBA ORPHAN NUCLEAR RECEPTOR/DNA COMPLEX (ORPHAN NUCLEAR RECEPTOR NR1D1)
reference	Khorasanizadeh et al. Mol.Cell 1 849 1998
source	Homo sapiens
experiment	X-ray (resolution=2.30, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
sequence family	Zinc finger, C4 type two domains;
multimeric complexes	1a6y_AB 1ga5_AB 1ga5_EF 1hlz_AB
redundant complexes	1ga5_B 1hlz_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1a6y_A interface=14,21,24,28,29,76, llckvcgdvasgfHygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrFgr
interface signature	HEKRRF

Estimated binding specificities ?

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# IC=4.456 IC/col=0.891 n_of_columns=5

specificity:

A |   0  36   0   0  12
C |   0  12  96  96  36
G |  96  24   0   0   0
T |   0  24   0   0  48

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Dendrogram of similar interfaces ?

matrix format

  
  --EAKG--KTRG--   L                            +4umm_A    
                            +-------------------1 
  ----KGVG--RG--   L        !                   +4tnt_B    
                       +----6 
  ----KGVT--RG--   L   !    !                    +5emc_A    
                       !    !                  +-2 
  --ECKGAGKGRG--   L   !    +------------------3 +1hcq_E    
                       !                       ! 
  --ECKGAGKTRG--   L --7                       +4aa6_B    
                       ! 
  CAECKG--KGRG--   L   !                   +----1cit_A    
                       !      +------------4 
  ----KGVT--RGRC   L   +------5            +----2c7a_B    
                              ! 
  --ECKGAG--RG--   L          +-----------------4ond_A

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updated Mon Jun 29 13:59:32 2026