1a6y_A : 3D-footprint complex

structure name	REVERBA ORPHAN NUCLEAR RECEPTOR/DNA COMPLEX (ORPHAN NUCLEAR RECEPTOR NR1D1)
reference	Khorasanizadeh et al. Mol.Cell 1 849 1998
source	Homo sapiens
experiment	X-ray (resolution=2.30, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
sequence family	Zinc finger, C4 type two domains;
multimeric complexes	1a6y_AB 1ga5_AB 1ga5_EF 1hlz_AB
redundant complexes	1ga5_B 1hlz_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1a6y_A interface=14,21,24,28,29,76, llckvcgdvasgfHygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrFgr
interface signature	HEKRRF

Estimated binding specificities ?

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# IC=5.188 IC/col=0.865 n_of_columns=6

specificity:

A |  59   0   0  19   0  67
C |   9   0   0   9  96  10
G |  19  96  96   9   0   0
T |   9   0   0  59   0  19

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Dendrogram of similar interfaces ?

matrix format

  
  --EAKG--KTRG--   L   +-----------------------------4umm_A    
                       ! 
  CAECKG--KGRG--   L   !                        +----1cit_A    
                     --5           +------------2 
  ----KGVT--RGRC   L   !   +-------3            +----2c7a_B    
                       !   !       ! 
  --ECKGAG--RG--   L   +---4       +-----------------4ond_A    
                           ! 
  --ECKGAGKGRG--   L       !                        +1hcq_E    
                           +------------------------1 
  --ECKGAGKTRG--   L                                +4aa6_B

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updated Sat Jan 10 04:26:17 2026