1ga5_EF : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA- BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT
reference	Rastinejad et al.
source	Homo sapiens
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1a6y_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1ga5_E interface=22,25,29,30,77,79, vllckvcgdvasgfhygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrFgRip > 1ga5_F interface=22,25,29,30,77, vllckvcgdvasgfhygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrFg
interface signature	EKRRFR/EKRRF

Estimated binding specificities ?

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# IC=10.147 IC/col=0.781 n_of_columns=13

specificity:

A |   9   0  73   7   0  24  24  24   7   0  88   0   0
C |   7   0   9  88  96  24  24  24   9   0   0  96  96
G |   7  88   7   0   0  24  24  24   7  96   1   0   0
T |  73   8   7   1   0  24  24  24  73   0   7   0   0

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updated Tue Jul 29 14:48:45 2025