1ga5_EF : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA- BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT
reference	Rastinejad et al.
source	Homo sapiens
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1a6y_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1ga5_E interface=22,25,29,30,77,79, vllckvcgdvasgfhygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrFgRip > 1ga5_F interface=22,25,29,30,77, vllckvcgdvasgfhygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrFg
interface signature	EKRRFR/EKRRF

Estimated binding specificities ?

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# IC=11.310 IC/col=0.870 n_of_columns=13

specificity:

A |   0   0   0   0  84  18  24  24   0   0   6   0  78
C |   0   0   0  96   6  60  24  24   0   0  12  96   6
G |  96  96   0   0   6  12  24  24  96  84  12   0   6
T |   0   0  96   0   0   6  24  24   0  12  66   0   6

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updated Wed Jun 24 09:21:11 2026