1hcq_AB : 3D-footprint complex

structure name	THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS
reference	Schwabe et al.
source	Homo sapiens
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1hcq_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1hcq_A interface=25,28,29,32,33, mketrycavcndyasgyhygvwscEgcKAffKRsiqghndymcpatnqctidknrrkscqacrlrkcyevgmmk > 1hcq_B interface=22,25,26,29,30, trycavcndyasgyhygvwscEgcKAffKRsiqghndymcpatnqctidknrrkscqacrlrkcyevgmmk
interface signature	EKAKR/EKAKR

Estimated binding specificities ?

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# IC=10.272 IC/col=0.790 n_of_columns=13

specificity:

A |   0   0   0   8  66  24  24  24   7   0  60   0   0
C |   0   0   0  88   7  24  24  24  14   0  22  96  96
G |  96  96   0   0  14  24  24  24   9  96   7   0   0
T |   0   0  96   0   9  24  24  24  66   0   7   0   0

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updated Sun Jan 4 21:22:06 2026