1hcq_AB : 3D-footprint complex

structure name	THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS
reference	Schwabe et al.
source	Homo sapiens
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1hcq_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1hcq_A interface=25,28,29,32,33, mketrycavcndyasgyhygvwscEgcKAffKRsiqghndymcpatnqctidknrrkscqacrlrkcyevgmmk > 1hcq_B interface=22,25,26,29,30, trycavcndyasgyhygvwscEgcKAffKRsiqghndymcpatnqctidknrrkscqacrlrkcyevgmmk
interface signature	EKAKR/EKAKR

Estimated binding specificities ?

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# IC=10.523 IC/col=0.809 n_of_columns=13

specificity:

A |   0   0   8   0  69  24  24  24   8   0  96   0   0
C |   0   0   8  96  11  24  24  24   8   0   0  96  96
G |  96  96  11   0   8  24  24  24   8  87   0   0   0
T |   0   0  69   0   8  24  24  24  72   9   0   0   0

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updated Wed Jun 24 09:26:02 2026