1hcq_EF : 3D-footprint complex

structure name	THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS
reference	Schwabe et al.
source	Homo sapiens
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1hcq_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1hcq_E interface=25,28,29,32,33, mketrycavcndyasgyhygvwscEgcKAffKRsiqghndymcpatnqctidknrrkscqacrlrkcyevgmmk > 1hcq_F interface=24,27,28,31,32, ketrycavcndyasgyhygvwscEgcKAffKRsiqgdymcpatnqctidknrrkscqacrlrkcyevgmmk
interface signature	EKAKR/EKAKR

Estimated binding specificities ?

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# IC=10.290 IC/col=0.792 n_of_columns=13

specificity:

A |   0   0   7   0  73  24  24  24   7   0  73   0   0
C |   0   0   7  96   7  24  24  24   7   0   9  96  96
G |  96  96   7   0   7  24  24  24   9  96   7   0   0
T |   0   0  75   0   9  24  24  24  73   0   7   0   0

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updated Tue Jul 29 14:53:13 2025