1hcq_EF : 3D-footprint complex

structure name	THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS
reference	Schwabe et al.
source	Homo sapiens
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1hcq_E
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1hcq_E interface=25,28,29,32,33, mketrycavcndyasgyhygvwscEgcKAffKRsiqghndymcpatnqctidknrrkscqacrlrkcyevgmmk > 1hcq_F interface=24,27,28,31,32, ketrycavcndyasgyhygvwscEgcKAffKRsiqgdymcpatnqctidknrrkscqacrlrkcyevgmmk
interface signature	EKAKR/EKAKR

Estimated binding specificities ?

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# IC=10.630 IC/col=0.818 n_of_columns=13

specificity:

A |   0   0  11   0  67  24  24  24   9   0  96   0   0
C |   0   0   9  96   9  24  24  24  11   0   0  96  96
G |  96  96   9   0  11  24  24  24   9  96   0   0   0
T |   0   0  67   0   9  24  24  24  67   0   0   0   0

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updated Sun Jan 4 21:22:17 2026