1hjb_ABC : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER
reference	Tahirov et al.
source	HOMO SAPIENS / MUS MUSCULUS
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	Leucine zipper domain;
reference complex	6mg1_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1hjb_A interface=11,14,17,18,21,22, dkhsdeykirRerNniAVrkSRdkakmrnletqhkvleltaenerlqkkveqlsrelstlrnlfkq > 1hjb_B interface=11,14,15,17,18,21,22, dkhsdeykirRerNNiAVrkSRdkakmrnletqhkvleltaenerlqkkveqlsrelstlrnlfkql > 1hjb_C interface=21,83,111,112,115,118, gelvrtdspnflcsvlpthwRcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitVDgpRepRrh
interface signature	RNAVSR/RNNAVSR/RRVDRR

Estimated binding specificities ?

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# IC=17.198 IC/col=0.905 n_of_columns=19

specificity:

A |   0   0   3   0   3  90  96  88  24  24  24   3   0   0   0   0   7   7   7
C |   0   0   6  96  84   0   0   3  24  24  24   3   0   0   0   0   9   7   5
G |   0   0   3   0   6   3   0   3  24  24  24   6  96   0  96  96   7   9  81
T |  96  96  84   0   3   3   0   2  24  24  24  84   0  96   0   0  73  73   3

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updated Mon Sep 9 12:25:19 2024