1hjb_DEF : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER
reference	Tahirov et al.
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	Leucine zipper domain;
reference complex	6mg1_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1hjb_D interface=11,14,18,21,22, dkhsdeykirRerNniaVrkSRdkakmrnletqhkvleltaenerlqkkveqlsrelstlrnlfkqlp > 1hjb_E interface=11,14,15,17,18,21,22, dkhsdeykirRerNNiAVrkSRdkakmrnletqhkvleltaenerlqkkveqlsrelstlrnlfkqlp > 1hjb_F interface=21,83,112,115,118, gelvrtdspnflcsvlpthwRcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitvDgpRepRrh
interface signature	RNVSR/RNNAVSR/RRDRR

Estimated binding specificities ?

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# IC=16.100 IC/col=0.894 n_of_columns=18

specificity:

A |   0   5   5   0   3  87  88  96  24  24  24   3   0   2   0   0   3   3
C |   0   3   7  96  85   3   5   0  24  24  24   3   0   3   0   0   5   3
G |   0   7   3   0   3   3   3   0  24  24  24   3  96   3  96  96   3   5
T |  96  81  81   0   5   3   0   0  24  24  24  87   0  88   0   0  85  85

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updated Mon Sep 9 12:25:39 2024