1hjb_DEF : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER
reference	Tahirov et al.
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	Leucine zipper domain;
reference complex	6mg1_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1hjb_D interface=11,14,18,21,22, dkhsdeykirRerNniaVrkSRdkakmrnletqhkvleltaenerlqkkveqlsrelstlrnlfkqlp > 1hjb_E interface=11,14,15,17,18,21,22, dkhsdeykirRerNNiAVrkSRdkakmrnletqhkvleltaenerlqkkveqlsrelstlrnlfkqlp > 1hjb_F interface=21,83,112,115,118, gelvrtdspnflcsvlpthwRcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitvDgpRepRrh
interface signature	RNVSR/RNNAVSR/RRDRR

Estimated binding specificities ?

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# IC=17.340 IC/col=0.963 n_of_columns=18

specificity:

A |   0   4  12   0   4  96  88  96   8  24  24   0   0   0   0   0   4   4
C |   0   0   8  96  84   0   0   0  68  24  24   4   0   0   0   0   4   4
G |   0  12   8   0   4   0   8   0   8  24  24   0  96   0  96  96   4   0
T |  96  80  68   0   4   0   0   0  12  24  24  92   0  96   0   0  84  88

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updated Sun Jan 4 21:23:05 2026