1hjb_DEF : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER
reference	Tahirov et al.
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	Leucine zipper domain;
reference complex	6mg1_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1hjb_D interface=11,14,18,21,22, dkhsdeykirRerNniaVrkSRdkakmrnletqhkvleltaenerlqkkveqlsrelstlrnlfkqlp > 1hjb_E interface=11,14,15,17,18,21,22, dkhsdeykirRerNNiAVrkSRdkakmrnletqhkvleltaenerlqkkveqlsrelstlrnlfkqlp > 1hjb_F interface=21,83,112,115,118, gelvrtdspnflcsvlpthwRcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitvDgpRepRrh
interface signature	RNVSR/RNNAVSR/RRDRR

Estimated binding specificities ?

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# IC=16.037 IC/col=0.891 n_of_columns=18

specificity:

A |  85  85   0   0  85   0  85  24  24  24   0   0   3   3   0  85  78  96
C |   5   5  96  96   5  96   1  24  24  24   0   7   5   5   0   3  12   0
G |   3   3   0   0   3   0   3  24  24  24   0   3   3  88  96   3   3   0
T |   3   3   0   0   3   0   7  24  24  24  96  86  85   0   0   5   3   0

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updated Tue Jul 29 14:54:03 2025