1hlz_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA- BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT
reference	Rastinejad et al.
source	Homo sapiens
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1a6y_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1hlz_A interface=22,25,29,30,79, vllckvcgdvasgfhygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrfgRip > 1hlz_B interface=24,27,31,32,79,81, gmvllckvcgdvasgfhygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrFgR
interface signature	EKRRR/EKRRFR

Estimated binding specificities ?

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# IC=16.233 IC/col=0.902 n_of_columns=18

specificity:

A |  81  96   8  24   2   0   0   0   0  93   5  24  24   0   0  19   0  96
C |   2   0  61  24   2   0   0   0  96   2  66  24  24   0   0  11  96   0
G |  11   0  17  24   2  96  96   0   0   0  23  24  24  96  96   8   0   0
T |   2   0  10  24  90   0   0  96   0   1   2  24  24   0   0  58   0   0

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updated Tue Jul 29 14:54:22 2025