1hlz_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA- BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT
reference	Rastinejad et al.
source	Homo sapiens
experiment	X-ray (resolution=2.80, R-factor=?)
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1hlz_A interface=22,25,29,30,79, vllckvcgdvasgfhygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrfgRip > 1hlz_B interface=24,27,31,32,79,81, gmvllckvcgdvasgfhygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrFgR
interface signature	EKRRR/EKRRFR

Estimated binding specificities ?

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# IC=13.540 IC/col=0.796 n_of_columns=17

specificity:

A |   4   0  65   0   0   8  24  24   4   0  82   0   0  74  24  24   0
C |   4   0  10  96  96   8  24  24   4   0   6  96  96   4  24  24   0
G |   4  96  13   0   0   8  24  24   0  96   4   0   0   5  24  24   0
T |  84   0   8   0   0  72  24  24  88   0   4   0   0  13  24  24  96

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updated Fri Dec 13 09:18:59 2024