1hlz_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE ORPHAN NUCLEAR RECEPTOR REV-ERB(ALPHA) DNA- BINDING DOMAIN BOUND TO ITS COGNATE RESPONSE ELEMENT
reference	Rastinejad et al.
source	Homo sapiens
experiment	X-ray (resolution=2.80, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	1a6y_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1hlz_A interface=22,25,29,30,79, vllckvcgdvasgfhygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrfgRip > 1hlz_B interface=24,27,31,32,79,81, gmvllckvcgdvasgfhygvlacEgcKgffRRsiqqniqykrclknencsivrinrnrcqqcrfkkclsvgmsrdavrFgR
interface signature	EKRRR/EKRRFR

Estimated binding specificities ?

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# IC=15.993 IC/col=0.889 n_of_columns=18

specificity:

A |  81  93  12  24  12   0   0   0   0  96   9  24  24   0   0   3   0  93
C |   3   0  54  24   0   0   0   3  96   0  54  24  24   0   0   3  96   3
G |   9   3  21  24   0  96  96   0   0   0  24  24  24  96  96   9   0   0
T |   3   0   9  24  84   0   0  93   0   0   9  24  24   0   0  81   0   0

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updated Mon Sep 9 12:26:07 2024