1imh_C : 3D-footprint complex

structure name	TONEBP/DNA COMPLEX (NUCLEAR FACTOR OF ACTIVATED T CELLS 5)
reference	Lopez-Rodriguez et al. Nat.Struct.Biol. 9 90 2002
source	Homo sapiens
experiment	X-ray (resolution=2.86, R-factor=0.244)
structural superfamily	E set domains;p53-like transcription factors;
sequence family	Rel homology domain RHD; IPT/TIG domain;
multimeric complexes	1imh_CD
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1imh_C interface=30,33,35,36,39,177, kkspmlcgqypvksegkelkivvqpetqhRarYlTEgsRgsvkdrtqqgfptvkleghnepvvlqvfvgndsgrvkphgfyqacrvtgrnttpckevdiegttvievgldpsnnmtlavdcvgilklrnadvearigiagskkkstrarlvfrvnimrkdgstltlqtpsspilctQpagvpeilkkslhscsvkgeeevfligknflkgtkvifqenvsdenswkseaeidmelfhqnhlivkvppyhdqhitlpvsvgiyvvtnagrshdvqpftytpd
interface signature	RYTERQ

Estimated binding specificities ?

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# IC=4.126 IC/col=0.825 n_of_columns=5

specificity:

A |  10  10   0   0  64
C |  10  10  96  96  10
G |  12   0   0   0  12
T |  64  76   0   0  10

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Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: TONEBP
GGAANNN	PubMed	1imh_C(1.08e-03)
TGGAAAGGACCAG	PubMed	1imh_C(1.89e-05)

Dendrogram of similar interfaces ?

matrix format

  
  RG--YTTTECRGQA----   L   +--------------1imh_C    
                           ! 
  RGRGYAEC--HG------   L --4            +-7w7l_B    
                           !         +--2 
  RCRCYCEC--HC----RG   L   !         !  +-1svc_P    
                           +---------3 
  RGRGYTEC----------   L             !    +1gji_A    
                                     +----1 
  RGRG--EC------KT--   L                  +2ram_A

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updated Fri Sep 13 15:40:56 2024