1io4_ABC : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN-CBFBETA CORE DOMAIN HETERODIMER AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER
reference	Tahirov et al.
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	Leucine zipper domain;
reference complex	6mg1_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1io4_A interface=10,13,14,16,17,20,21, khsdeykirRerNNiAVrkSRdkakmrnletqhkvleltaenerlqkkveqlsrelstlrnlf > 1io4_B interface=14,17,18,20,21,24,25, ktvdkhsdeykirRerNNiAVrkSRdkakmrnletqhkvleltaenerlqkkveqlsrelstlrnlfkql > 1io4_C interface=21,83,111,112,115,118, gelvrtdspnflcsvlpthwRcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitVDgpRepRrh
interface signature	RNNAVSR/RNNAVSR/RRVDRR

Estimated binding specificities ?

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# IC=15.047 IC/col=0.885 n_of_columns=17

specificity:

A |   0   0   0   0  10  75  96  81  24  24  24   0   0   0   0   0   5
C |   0  25   0  96  75   5   0   5  24  24  24  10   0   0   0   0   5
G |   0   1   0   0   5  10   0   5  24  24  24   0  96   0  96  96  10
T |  96  70  96   0   6   6   0   5  24  24  24  86   0  96   0   0  76

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updated Sun Jan 4 21:28:02 2026