1io4_ABC : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN-CBFBETA CORE DOMAIN HETERODIMER AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER
reference	Tahirov et al.
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	Leucine zipper domain;
reference complex	6mg1_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1io4_A interface=10,13,14,16,17,20,21, khsdeykirRerNNiAVrkSRdkakmrnletqhkvleltaenerlqkkveqlsrelstlrnlf > 1io4_B interface=14,17,18,20,21,24,25, ktvdkhsdeykirRerNNiAVrkSRdkakmrnletqhkvleltaenerlqkkveqlsrelstlrnlfkql > 1io4_C interface=21,83,111,112,115,118, gelvrtdspnflcsvlpthwRcnktlpiafkvvalgdvpdgtlvtvmagndenysaelrnataamknqvarfndlrfvgrsgRgksftltitvftnppqvatyhraikitVDgpRepRrh
interface signature	RNNAVSR/RNNAVSR/RRVDRR

Estimated binding specificities ?

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# IC=14.838 IC/col=0.873 n_of_columns=17

specificity:

A |  90   0   0  96   0  76  24  24  24   5   0   5   5   0  96  65  96
C |   1  96  96   0  96  10  24  24  24  10   0  10  10   0   0   0   0
G |   0   0   0   0   0   5  24  24  24   6   0   6  75  96   0  26   0
T |   5   0   0   0   0   5  24  24  24  75  96  75   6   0   0   5   0

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updated Wed Jun 24 09:32:16 2026