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structure name3D SOLUTION NMR STRUCTURE OF THE M9I MUTANT OF THE HMG-BOX DOMAIN OF THE HUMAN MALE SEX DETERMINING FACTOR SRY COMPLEXED TO DNA
(SEX-DETERMINING REGION Y PROTEIN)
sourceHOMO SAPIENS
experimentNMR
structural superfamilyHMG-box;
sequence familyHMG high mobility group box;
redundant complexes1j46
reference complex1hry_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNFIRNSSYPR

Estimated binding specificities ?

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# IC=4.718 IC/col=0.786 n_of_columns=6 specificity:   
A |   0   0   6   6   0   6
C |   0   1   6   6   8   6
G |  89  12   6   8  76   6
T |   7  83  78  76  12  78
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: SRY
AACAATPubMed1j47_A(1.13e-03), 1j46_A(3.39e-03)
AACAAAGPubMed1j47_A(6.45e-06), 1j46_A(5.20e-05)
TCAAAGPubMed1j47_A(1.14e-03), 1j46_A(3.39e-03)
ACAATPubMed1j47_A(3.57e-04), 1j46_A(1.01e-03)
ATTGTTPubMed1j47_A(1.13e-03), 1j46_A(3.39e-03)
CTTTGPubMed1j47_A(3.63e-04), 1j46_A(1.01e-03)
GAACAATPubMed1j47_A(3.39e-03), 1j46_A(1.05e-02)
NACAATPubMed1j47_A(1.13e-03), 1j46_A(3.39e-03)

Dendrogram of similar interfaces ?

matrix format



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updated Thu Sep 12 14:45:49 2024