interface graph thumbnail
legend  pdf

structure namePURINE REPRESSOR MUTANT-HYPOXANTHINE-PURF OPERATOR COMPLEX
(PURINE NUCLEOTIDE SYNTHESIS REPRESSOR)
referenceHuffman et al. Biochemistry 41 511 2002
sourceEscherichia coli
experimentX-ray (resolution=2.55, R-factor=0.219)
structural superfamilyPeriplasmic binding protein-like I;lambda repressor-like DNA-binding domains;
sequence familyPeriplasmic binding proteins and sugar b; Bacterial regulatory proteins, lacI fami;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSTTRLK

Estimated binding specificities ?

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# IC=7.181 IC/col=0.898 n_of_columns=8 specificity:   
A |   0   0  96  57  24  96   0  13
C |  96   0   0  13  24   0  96  13
G |   0  96   0  13  24   0   0  57
T |   0   0   0  13  24   0   0  13
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updated Mon Dec 16 17:57:57 2024