| structure name | HUMAN PAPILLOMAVIRUS TYPE 18 E2 DNA-BINDING DOMAIN BOUND TO ITS DNA TARGET (Regulatory protein E2) |
| reference | Hegde et al. J.Biol.Chem. 275 31245 2000 |
| source | Human papillomavirus type 18 |
| experiment | X-ray (resolution=2.40, R-factor=0.210) |
| structural superfamily | Viral DNA-binding domain; |
| sequence family | E2 early protein, C terminal; |
| multimeric complexes | 1jj4_AB |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | NKCYR |
Estimated binding specificities ?
| readout + contact |  |
A | 8 0 0 0 11 8 C | 69 0 0 0 8 8 G | 8 96 88 0 8 72 T | 11 0 8 96 69 8scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: E2 | ||
| ACCGN | PubMed | 1jj4_B(3.68e-04) |
| ATCGGTG | PubMed | 1jj4_B(3.47e-03) |
| AACGAATTCGTT | PubMed | 1jj4_AB(1.13e-04) |
| AACCGN | PubMed | 1jj4_B(9.28e-07), 1jj4_AB(3.69e-04) |
Dendrogram of similar interfaces ?
matrix format----------------KGCG------------------------------ L +----------2bop_A +---------5 ----------KGTA--YCNG------------------------------ L +--------6 +----------5t7x_B ! ! ------------------------------------------RC------ L ! +--------------------2itl_B ! RGKGTTTC------------------IGACNAAT---------------- L +-7 +5t8d_A ! ! +-2 RG--------------------------TAAAVA--QT------------ L ! ! ! +5t2o_A ! +---------------------------4 QTFAQGNG--------------------HCSCLA--QG--QA-------- L ! ! +4yit_A --8 ! +-1 --RGVTSA--------------------FCMCST--QT--EC-------- L ! +-3 +5esp_A ! ! QA--KTTG------------------RAETRG--AT--DT---------- L ! +4lq0_A ! --------KG----QG--RGHTRTQT------------------AATTRT +-----------------------------5ond_B |
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updated Fri Sep 13 15:43:03 2024