1k78_EF : 3D-footprint complex

structure name	PAX5(1-149)+ETS-1(331-440)+DNA
reference	Wolberger et al. Mol.Cell 8 1267 2001
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=2.25, R-factor=?)
structural superfamily	Homeodomain-like;
reference complex	1k78_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1k78_E interface=11,43,44,48,49,65,68,113,115,119, gvnqlggvfvNgrplpdvvrqrivelahqgvrpcdisrqlrvSHgcvSKilgryyetgsikpgvIggSkpkvatpkvvekiaeykrqnptmfaweirdrllaervcdndtvpSvSsinRiirtk > 1k78_F interface=54,55,58,61,62, piqlwqfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyEKlsRglRYyydkniihktagkryvyrfvcdlqsllgytpeelhamldvk
interface signature	NSHSKISSSR/EKRRY

Estimated binding specificities ?

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# IC=10.589 IC/col=0.504 n_of_columns=21

specificity:

A |   7  24   0  11  24  24   8  24  24  24  24   5  24  24  24   0   0   0   0   0   0
C |   7  24  89  66  24  24  11  24  24  24  24  59  24  24  24   3  96   0  96  96   0
G |   7  24   0  12  24  24  11  24  24  24  24  25  24  24  24   5   0   0   0   0  96
T |  75  24   7   7  24  24  66  24  24  24  24   7  24  24  24  88   0  96   0   0   0

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updated Wed Jun 24 09:36:52 2026