1k78_EF : 3D-footprint complex

structure name	PAX5(1-149)+ETS-1(331-440)+DNA
reference	Wolberger et al. Mol.Cell 8 1267 2001
source	MUS MUSCULUS / HOMO SAPIENS
experiment	X-ray (resolution=2.25, R-factor=?)
structural superfamily	Homeodomain-like;
reference complex	1k78_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1k78_E interface=11,43,44,48,49,65,68,113,115,119, gvnqlggvfvNgrplpdvvrqrivelahqgvrpcdisrqlrvSHgcvSKilgryyetgsikpgvIggSkpkvatpkvvekiaeykrqnptmfaweirdrllaervcdndtvpSvSsinRiirtk > 1k78_F interface=54,55,58,61,62, piqlwqfllelltdkscqsfiswtgdgwefklsdpdevarrwgkrknkpkmnyEKlsRglRYyydkniihktagkryvyrfvcdlqsllgytpeelhamldvk
interface signature	NSHSKISSSR/EKRRY

Estimated binding specificities ?

readout + contact

# IC=9.489 IC/col=0.499 n_of_columns=19

specificity:

A |   0   0   0  96   0  76  24  24  24  11  24  24  24  24  67  24  24  14   4
C |  96   0   0   0   0   4  24  24  24  19  24  24  24  24   4  24  24   9   6
G |   0  96  96   0  96  12  24  24  24  62  24  24  24  24   9  24  24  62  86
T |   0   0   0   0   0   4  24  24  24   4  24  24  24  24  16  24  24  11   0

scan!

home
updated Tue Jul 29 15:02:48 2025