1lws_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE INTEIN HOMING ENDONUCLEASE PI-SCEI BOUND TO ITS RECOGNITION SEQUENCE (ENDONUCLEASE PI-SCEI)
reference	Quiocho et al.
source	Saccharomyces cerevisiae
experiment	X-ray (resolution=3.50, R-factor=?)
structural superfamily	Hedgehog/intein Hint domain;Homing endonucleases;
sequence family	Hom_endassociated Hint; Homing endonuclease;
reference complex	1lwt_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1lws_A interface=55,57,90,94,96,101,125,127,165,166,216,219,301,306,309,313,337,339,344,348,350,353,357, cfakgtnvlmadgsiecienievgnkvmgkdgrpreviklprgretmysvvqksQhRahksdssrevpellkftcnathelvvrtprsvRrlsRtIkgvfEvitfemgqkkapdgrivelvkevSkSypisperanelvesyrkasnkayfewtieardlsllgSHvrkatyqtyapilyendhffdymqkskfhltiegpkvlayllglwigdgLsdRatfsvdsrdtslmervteyaeklnlcavaktvnlysenplwdaivglgflkdgvknipsflstdnigtretflaglidsdgYvtdeHgiKatiKtihtsvrdglvslarslglvvsvNaEpakvDmngTkHkiSyaiYmsggdvllnvlskcagskkfrpapaaafarecrgfyfelqelkeddyygitlsddsdhqfllanqvvvhn
interface signature	QRRRIESSSHLRYHKKNEDTHSY

Estimated binding specificities ?

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# IC=18.259 IC/col=0.794 n_of_columns=23

specificity:

A |   0  48  72   0   3  24  24  24  24   0   0   0   5   1   0  57  69   0   0  96  24  24   0
C |   0  34  12   0   3  24  24  24  24  96   0   0   1  86   0  38  17   0  96   0  24  24   0
G |   0   5   9   0   3  24  24  24  24   0   0   0   2   1   0   1   7  96   0   0  24  24   0
T |  96   9   3  96  87  24  24  24  24   0  96  96  88   8  96   0   3   0   0   0  24  24  96

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updated Sun Jun 28 03:52:16 2026