1lws_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE INTEIN HOMING ENDONUCLEASE PI-SCEI BOUND TO ITS RECOGNITION SEQUENCE (ENDONUCLEASE PI-SCEI)
reference	Quiocho et al.
source	Saccharomyces cerevisiae
experiment	X-ray (resolution=3.50, R-factor=?)
structural superfamily	Hedgehog/intein Hint domain;Homing endonucleases;
sequence family	Hom_endassociated Hint; Homing endonuclease;
reference complex	1lwt_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1lws_A interface=55,57,90,94,96,101,125,127,165,166,216,219,301,306,309,313,337,339,344,348,350,353,357, cfakgtnvlmadgsiecienievgnkvmgkdgrpreviklprgretmysvvqksQhRahksdssrevpellkftcnathelvvrtprsvRrlsRtIkgvfEvitfemgqkkapdgrivelvkevSkSypisperanelvesyrkasnkayfewtieardlsllgSHvrkatyqtyapilyendhffdymqkskfhltiegpkvlayllglwigdgLsdRatfsvdsrdtslmervteyaeklnlcavaktvnlysenplwdaivglgflkdgvknipsflstdnigtretflaglidsdgYvtdeHgiKatiKtihtsvrdglvslarslglvvsvNaEpakvDmngTkHkiSyaiYmsggdvllnvlskcagskkfrpapaaafarecrgfyfelqelkeddyygitlsddsdhqfllanqvvvhn
interface signature	QRRRIESSSHLRYHKKNEDTHSY

Estimated binding specificities ?

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# IC=18.156 IC/col=0.789 n_of_columns=23

specificity:

A |  93  24  24   0   0   4   2   4  88   7  91  96  96   0  24  24  24  24  93  96  12   0  96
C |   0  24  24   0   0  88   3   2   2   5   3   0   0   0  24  24  24  24   0   0  12   0   0
G |   1  24  24   0  96   2   7  16   2  72   0   0   0  96  24  24  24  24   2   0  12  12   0
T |   2  24  24  96   0   2  84  74   4  12   2   0   0   0  24  24  24  24   1   0  60  84   0

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updated Sat Aug 2 01:08:23 2025