1lws_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE INTEIN HOMING ENDONUCLEASE PI-SCEI BOUND TO ITS RECOGNITION SEQUENCE (ENDONUCLEASE PI-SCEI)
reference	Quiocho et al.
source	Saccharomyces cerevisiae
experiment	X-ray (resolution=3.50, R-factor=?)
structural superfamily	Hedgehog/intein Hint domain;Homing endonucleases;
sequence family	Hom_endassociated Hint; Homing endonuclease;
reference complex	1lwt_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1lws_A interface=55,57,90,94,96,101,125,127,165,166,216,219,301,306,309,313,337,339,344,348,350,353,357, cfakgtnvlmadgsiecienievgnkvmgkdgrpreviklprgretmysvvqksQhRahksdssrevpellkftcnathelvvrtprsvRrlsRtIkgvfEvitfemgqkkapdgrivelvkevSkSypisperanelvesyrkasnkayfewtieardlsllgSHvrkatyqtyapilyendhffdymqkskfhltiegpkvlayllglwigdgLsdRatfsvdsrdtslmervteyaeklnlcavaktvnlysenplwdaivglgflkdgvknipsflstdnigtretflaglidsdgYvtdeHgiKatiKtihtsvrdglvslarslglvvsvNaEpakvDmngTkHkiSyaiYmsggdvllnvlskcagskkfrpapaaafarecrgfyfelqelkeddyygitlsddsdhqfllanqvvvhn
interface signature	QRRRIESSSHLRYHKKNEDTHSY

Estimated binding specificities ?

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# IC=17.878 IC/col=0.777 n_of_columns=23

specificity:

A |  87  24  24   0   0   0   1   2  91   4  89  96  96   0  24  24  24  24  88  96   8   2  96
C |   5  24  24   0   0  91   2   2   2   8   3   0   0   0  24  24  24  24   2   0  12   4   0
G |   4  24  24   0  96   3   6  25   0  76   2   0   0  96  24  24  24  24   2   0   8  16   0
T |   0  24  24  96   0   2  87  67   3   8   2   0   0   0  24  24  24  24   4   0  68  74   0

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updated Thu Jan 8 18:17:01 2026