1mj2_ABCD : 3D-footprint complex

structure name	METHIONINE REPRESSOR MUTANT (Q44K) PLUS COREPRESSOR (S-ADENOSYL METHIONINE) COMPLEXED TO A CONSENSUS OPERATOR SEQUENCE
reference	Phillips et al. 'Structure 8 905 2000
source	Escherichia coli
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	Ribbon-helix-helix;
reference complex	1mjo_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1mj2_A interface=23,25,27, aewsgeyispyaehgkkseqvkKiTvSiplkvlkiltdertrrkvnnlrhatnsellceaflhaftgqplpddadlrkersdeipeaakeimremginpetwey > 1mj2_B interface=23,25,27, aewsgeyispyaehgkkseqvkKiTvSiplkvlkiltdertrrkvnnlrhatnsellceaflhaftgqplpddadlrkersdeipeaakeimremginpetwey > 1mj2_C interface=23,25,27, aewsgeyispyaehgkkseqvkKiTvSiplkvlkiltdertrrkvnnlrhatnsellceaflhaftgqplpddadlrkersdeipeaakeimremginpetwey > 1mj2_D interface=23,25,27, aewsgeyispyaehgkkseqvkKiTvSiplkvlkiltdertrrkvnnlrhatnsellceaflhaftgqplpddadlrkersdeipeaakeimremginpetwey
interface signature	KTS/KTS/KTS/KTS

Estimated binding specificities ?

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# IC=14.945 IC/col=0.934 n_of_columns=16

specificity:

A |  72   0  65   1   9   0   0   1  82   0  96  24   9  80   0   1
C |   0   0   1  82   3   2  96  29   1   0   0  24   0   1  96  40
G |  21  96   4   0  84   0   0   1  11  96   0  24  86   1   0   0
T |   3   0  26  13   0  94   0  65   2   0   0  24   1  14   0  55

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updated Wed Jun 24 10:12:14 2026