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structure nameMETHIONINE HOLOREPRESSOR MUTANT (Q44K) PLUS COREPRESSOR (S-ADENOSYL METHIONINE) COMPLEXED TO THE MINIMAL MET CONSENSUS OPERATOR WITH THE CENTRAL TA STEP MUTATED TO AT
(METHIONINE REPRESSOR)
referencePhillips et al. 'Structure 8 905 2000
sourceEscherichia coli
experimentX-ray (resolution=2.10, R-factor=0.189)
structural superfamilyRibbon-helix-helix;
sequence familyMet Aporepressor, MetJ;
multimeric complexes1cma_AB 1mj2_ABCD 1mjm_AB 1mjo_ABCD 1mjp_AB 1mjq_ABCD 1mjq_GHIJ
redundant complexes1cma_A 1mj2_A 1mjm_B 1mjp_A 1mjq_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKT

Estimated binding specificities ?

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# IC=3.803 IC/col=0.543 n_of_columns=7 specificity:   
A |  37   0  44  24  40   5   7
C |   0   0  13  24   7   5  71
G |  59  96  23  24  42   2   5
T |   0   0  16  24   7  84  13
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updated Tue Dec 19 05:55:06 2023