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structure nameMETHIONINE HOLOREPRESSOR MUTANT (Q44K) PLUS COREPRESSOR (S-ADENOSYL METHIONINE) COMPLEXED TO THE MINIMAL MET CONSENSUS OPERATOR WITH THE CENTRAL TA STEP MUTATED TO AT
(METHIONINE REPRESSOR)
referencePhillips et al. 'Structure 8 905 2000
sourceEscherichia coli
experimentX-ray (resolution=2.10, R-factor=0.189)
structural superfamilyRibbon-helix-helix;
sequence familyMet Aporepressor, MetJ;
multimeric complexes1cma_AB 1mj2_ABCD 1mjm_AB 1mjo_ABCD 1mjp_AB 1mjq_ABCD 1mjq_GHIJ
redundant complexes1cma_A 1mj2_A 1mjm_B 1mjp_A 1mjq_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKT

Estimated binding specificities ?

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# IC=2.250 IC/col=0.321 n_of_columns=7 specificity:   
A |   9  73  24  24  24   7   7
C |   7   9  24  24  24  73   7
G |  73   7  24  24  24   7   9
T |   7   7  24  24  24   9  73
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updated Fri Sep 13 15:49:55 2024