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structure nameMETHIONINE HOLOREPRESSOR MUTANT (Q44K) PLUS COREPRESSOR (S-ADENOSYL METHIONINE) COMPLEXED TO THE MINIMAL MET CONSENSUS OPERATOR WITH THE CENTRAL TA STEP MUTATED TO AT
(METHIONINE REPRESSOR)
referencePhillips et al. 'Structure 8 905 2000
sourceEscherichia coli
experimentX-ray (resolution=2.10, R-factor=0.189)
structural superfamilyRibbon-helix-helix;
sequence familyMet Aporepressor, MetJ;
multimeric complexes1cma_AB 1mj2_ABCD 1mjm_AB 1mjo_ABCD 1mjp_AB 1mjq_ABCD 1mjq_GHIJ
redundant complexes1cma_A 1mj2_A 1mjm_B 1mjp_A 1mjq_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKT

Estimated binding specificities ?

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# IC=4.239 IC/col=0.606 n_of_columns=7 specificity:   
A |  24   0  37  24  24  21   3
C |   3   0  18  24   0   1  71
G |  69  96  26  24  71   0   1
T |   0   0  15  24   1  74  21
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updated Sat Jan 10 04:48:30 2026