1mnm_A : 3D-footprint complex

structure name	YEAST MATALPHA2/MCM1/DNA TERNARY TRANSCRIPTION COMPLEX CRYSTAL STRUCTURE (PROTEIN MCM1 TRANSCRIPTIONAL REGULATOR)
reference	Richmond et al.
source	SACCHAROMYCES CEREVISIAE
experiment	X-ray (resolution=2.25, R-factor=0.240)
structural superfamily	SRF-like;
sequence family	SRFtype transcription factor DNAbinding a;
multimeric complexes	1mnm_ABCD
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1mnm_A interface=5,16,20,24, qkerRkieikfienkTrrhVtfsKrkhgimkkafelsvltgtqvlllvvsetglvytfstpkfepivtqqegrnliqaclnapdd
interface signature	RTVK

Estimated binding specificities ?

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# IC=3.142 IC/col=0.786 n_of_columns=4

specificity:

A |  13   0  13  96
C |  54  96  13   0
G |  13   0  13   0
T |  16   0  57   0

scan!

Related DNA sequences reported in the literature ?

site	source	matches (E-value)
term: MCM1
GGAAA	PubMed	1mnm_ABCD(7.77e-05)
CCTAATTAGG	PubMed	1mnm_A(4.16e-03), 1mnm_ABCD(1.09e-02)
CCCTAAAAGG	PubMed	1mnm_A(4.16e-03)

Dendrogram of similar interfaces ?

matrix format

  
  --RTTT--VTKG   L            +-1mnm_A    
                     +--------1 
  RA----YA--KG   L   !        +-1hbx_D    
                   --3 
  RT--------KA       !   +------1n6j_A    
                     +---2 
  RT--------KA           +------1egw_B

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updated Fri Sep 13 15:50:07 2024