interface graph thumbnail
legend  pdf

structure nameHUMAN TOPOISOMERASE I ARA-C COMPLEX
(DNA topoisomerase I)
referenceChrencik et al. J.Biol.Chem. 278 12461 2003
sourceHomo sapiens
experimentX-ray (resolution=3.10, R-factor=0.235)
structural superfamilyEukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment;DNA breaking-rejoining enzymes;
sequence familyEukaryotic DNA topoisomerase I, DNA bind; Eukaryotic DNA topoisomerase I, catalyti;
reference complex1a31_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


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updated Mon Dec 18 05:28:35 2023