| structure name | HUMAN RECONSTITUTED DNA TOPOISOMERASE I IN COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX (PROTEIN TOPOISOMERASE I) |
| reference | Champoux et al. Science 279 1504 1998 |
| source | Homo sapiens |
| experiment | X-ray (resolution=2.10, R-factor=0.247) |
| structural superfamily | DNA breaking-rejoining enzymes;Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment; |
| sequence family | Eukaryotic DNA topoisomerase I, DNA bind; Eukaryotic DNA topoisomerase I, catalyti; |
| redundant complexes | 1a35_A
1a36_A
1ej9_A
1lpq_A
 1r49_A
1rr8_C
1rrj_A
|
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence |
No structural evidence for specific binding to DNA (<4 informative columns)
Dendrogram of similar interfaces ?
matrix format--RG--YAMC--------NC----KA------------NT L +---1a31_A +-------------1 NTRGMGYAMC--KT----NC----KTDA------TT---- L ! +---2b9s_A +------3 ------YC--YT--RT--KGKG--KT------ETRGYG-- L ! ! +------------2h7g_X --4 +----2 ----------------RG----------RG---------- L ! +------------3m4a_A ! ----------------------KA------RA-------- L +------------------------1xo0_B |
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updated Sun Aug 3 05:17:24 2025