1r4r_AB : 3D-footprint complex

structure name	CRYSTALLOGRAPHIC ANALYSIS OF THE INTERACTION OF THE GLUCOCORTICOID RECEPTOR WITH DNA
reference	Otwinowski et al. Nature 352 497 1991
source	Rattus norvegicus
experiment	X-ray (resolution=3.00, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	3g9m_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1r4r_A interface=24,25,28,29, rpclvcsdeasgchygvltcgscKVffKRavegqhnylcagrndciidkirrkncpacryrkclqagmnlear > 1r4r_B interface=18,28,29,33, mkparpclvcsdeasgcHygvltcgscKVffkRavegqhnylcagrndciidkirrkncpacryrkclqagmnlear
interface signature	KVKR/HKVR

Estimated binding specificities ?

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# IC=6.633 IC/col=0.603 n_of_columns=11

specificity:

A |  67   0  67  24  24  24   0   0   0  24   9
C |   9  96  11  24  24  24   0   0   0  24  67
G |   9   0   9  24  24  24   0  96   0  24   9
T |  11   0   9  24  24  24  96   0  96  24  11

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updated Tue Jul 29 16:35:21 2025