1rep_C : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF REPLICATION INITIATOR PROTEIN REPE54 OF MINI-F PLASMID COMPLEXED WITH AN ITERON DNA (PROTEIN REPLICATION INITIATION PROTEIN)
reference	Matsunaga et al.
source	Escherichia coli
experiment	X-ray (resolution=2.60, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
sequence family	Initiator Replication protein;
multimeric complexes	2z9o_AB
redundant complexes	2z9o
reference complex	8ac8_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1rep_C interface=55,56,57,59,60,63,92,165,166,168,170,171,174,175,201, sprivqsndlteaayslsrdqkrmlylfvdqirkshdgiceihvakyaeifgltSAEaSKdiRqalksfagkevvfyesfpwfikpahspsRglysvhinpylipffiglqnrftqfrlsetkeitnpyamrlyeslcqyrkpdgsgivslkidwiieryqlpqSYqRmPDfrRRflqvcvneinsrtpmrlsyiekkkgRqtthivfsfrdit
interface signature	SAESKRRSYRPDRRR

Estimated binding specificities ?

readout + contact

# IC=12.091 IC/col=0.711 n_of_columns=17

specificity:

A |   0   0   0   0  96   0  84  24  24  24  24  12   0  24  56  24   4
C |   0   0   0   0   0  96   4  24  24  24  24  16  96  24  16  12  88
G |   0  96   0  96   0   0   4  24  24  24  24  64   0  24  12   8   0
T |  96   0  96   0   0   0   4  24  24  24  24   4   0  24  12  52   4

scan!

Dendrogram of similar interfaces ?

matrix format

  
  ------SGAAECSAKGRG----RG--STYGRTPGDCRGRGRC   L         +--------------------1rep_C    
                                                   +-----2 
  ----TT--PTTCSTNT--------RT----------------   L   !     !  +-----------------4lln_I    
                                                 --3     +--1 
  LTETTTRAECRCRCQC--------------------------   L   !        +-----------------3n97_A    
                                                   ! 
  ----------------RGHTST--------------------   L   +--------------------------6akp_C

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updated Thu Sep 12 15:25:31 2024