| structure name | STRUCTURAL MECHANISMS OF CAMPTOTHECIN RESISTANCE BY MUTATIONS IN HUMAN TOPOISOMERASE I (DNA topoisomerase I) |
| reference | Chrencik et al. J.Mol.Biol. 339 773 2004 |
| source | Homo sapiens |
| experiment | X-ray (resolution=2.60, R-factor=0.292) |
| structural superfamily | Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment;DNA breaking-rejoining enzymes; |
| sequence family | Eukaryotic DNA topoisomerase I, DNA bind; Eukaryotic DNA topoisomerase I, catalyti; |
| reference complex | 1a31_A |
| links to other resources | NAKB PDIdb DNAproDB |
| protein sequence | |
| interface signature | ERKYMKNKN |
Estimated binding specificities ?
| contact | ![]() |
A | 96 13 0 0 13 C | 0 54 0 0 13 G | 0 16 0 0 54 T | 0 13 96 96 16scan! |
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updated Sat Aug 2 01:47:59 2025


