1srs_AB : 3D-footprint complex

structure name	SERUM RESPONSE FACTOR (SRF) CORE COMPLEXED WITH SPECIFIC SRE DNA
reference	Pellegrini et al. Nature 376 490 1995
source	Homo sapiens
experiment	X-ray (resolution=3.20, R-factor=?)
structural superfamily	SRF-like;
reference complex	1hbx_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1srs_A interface=1,4,24, TrgRvkikmefidnklrryttfsKrktgimkkayelstltgtqvlllvasetghvytfatrklqpmitsetgkaliqtclnspd > 1srs_B interface=1,4,20,23,24, TrgRvkikmefidnklrryTtfSKrktgimkkayelstltgtqvlllvasetghvytfatrklqpmitsetgkaliqtcl
interface signature	TRK/TRTSK

Estimated binding specificities ?

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# IC=8.773 IC/col=0.877 n_of_columns=10

specificity:

A |  36   6   3  96  63  15   3  92   0   0
C |  55  86   1   0   5  21   1   0   0   0
G |   4   1  15   0  15  15   6   3  96  96
T |   1   3  77   0  13  45  86   1   0   0

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updated Sun Jan 4 23:37:24 2026