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legend  pdf

structure nameTERNARY COMPLEX OF SAP-1 AND SRF WITH SPECIFIC SRE DNA
(SERUM RESPONSE FACTOR)
referenceRichmond et al. 'Embo 20 3018 2001
sourceHOMO SAPIENS
experimentX-ray (resolution=3.15, R-factor=0.252)
structural superfamilySRF-like;
sequence familySRFtype transcription factor DNAbinding a;
multimeric complexes1hbx_ABG 1hbx_DH 1k6o_ABC 1srs_AB
redundant complexes1k6o_C 1srs_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureTRYK

Estimated binding specificities ?

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# IC=6.633 IC/col=0.737 n_of_columns=9 specificity:   
A |   0   0  67   0   0  67  24  24  11
C |   0   0   9   0   0   9  24  24   9
G |   0   0   9  96  96  11  24  24   9
T |  96  96  11   0   0   9  24  24  67
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Dendrogram of similar interfaces ?

matrix format
  
  TCRA--YA----KG   L                 +1hbx_A    
                       +-------------2 
  TCRT------STKT   L   !             +1k6o_B    
                     --3 
  --RT--------KA       !              +1n6j_A    
                       +--------------1 
  --RTRC--VC--KG   L                  +6wc2_D    
                     

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updated Fri Sep 13 15:38:23 2024