1hbx_A : 3D-footprint complex

structure name	TERNARY COMPLEX OF SAP-1 AND SRF WITH SPECIFIC SRE DNA (SERUM RESPONSE FACTOR)
reference	Richmond et al. 'Embo 20 3018 2001
source	HOMO SAPIENS
experiment	X-ray (resolution=3.15, R-factor=0.252)
structural superfamily	SRF-like;
sequence family	SRFtype transcription factor DNAbinding a;
multimeric complexes	1hbx_ABG 1hbx_DH 1k6o_ABC 1srs_AB
redundant complexes	1k6o_C 1srs_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 1hbx_A interface=4,7,22,27, gkkTrgRvkikmefidnklrrYttfsKrktgimkkayelstltgtqvlllvasetghvytfatrklqpmitsetgkaliqtclnspd
interface signature	TRYK

Estimated binding specificities ?

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# IC=6.672 IC/col=0.741 n_of_columns=9

specificity:

A |   0   0  67   0   0  69  24  24  11
C |   0   0   9   0   0   9  24  24   9
G |   0   0   9  96  96   9  24  24   9
T |  96  96  11   0   0   9  24  24  67

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Dendrogram of similar interfaces ?

matrix format

  
  TCRA--YA----KG   L                 +1hbx_A    
                       +-------------2 
  TCRT------STKT   L   !             +1k6o_B    
                     --3 
  --RT--------KA       !              +1n6j_A    
                       +--------------1 
  --RTRC--VC--KG   L                  +6wc2_D

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updated Sun Aug 3 05:34:49 2025